Evidence map›Paper›PMID 35051059›Full record

ReviewToxics2022

A Review of Associations between Externalizing Behaviors and Prenatal Cannabis Exposure: Limitations & Future Directions.

Ami S Ikeda, Valerie S Knopik, L Cinnamon Bidwell, Stephanie H Parade, Sherryl H Goodman, Eugene K Emory, Rohan H C Palmer

Open access · goldAbstract readReview
In one paragraph

Review in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ami S IkedaBehavioral Genetics of Addiction Laboratory, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-1515-4139
Valerie S KnopikDepartment of Human Development and Family Studies, College of Health and Human Sciences, Purdue University, West Lafayette, IN 47907, USA.
L Cinnamon BidwellInstitute of Cognitive Science, University of Colorado Boulder, Boulder, CO 80309, USA.
Stephanie H ParadeDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI 02903, USA.
Sherryl H GoodmanDepartment of Psychology, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-6653-2961
Eugene K EmoryDepartment of Psychology, Emory University, Atlanta, GA 30322, USA.
Rohan H C PalmerBehavioral Genetics of Addiction Laboratory, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-6809-9962
Emory University · USBrown University · USPurdue University West Lafayette · USUniversity of Colorado Boulder · US

Funding

Longitudinal examination of DNA methylation in maltreated childrenR01HD095837 · NICHD · EMMA PENDLETON BRADLEY HOSPITAL · PI PARADE, STEPHANIE HART · 2018 to 2022
$2.8M
NICHD NIH HHS R01 HD095837
6 · The paper itself

Abstract

In utero cannabis exposure can disrupt fetal development and increase risk for various behavioral disruptions, including hyperactivity, inattention, delinquent behaviors, and later substance abuse, among others. This review summarizes the findings from contemporary investigations linking prenatal cannabis exposure to the development of psychopathology and identifies the limitations within the literature, which constrain our interpretations and generalizability. These limitations include a lack of genetic/familial control for confounding and limited data examining real world products, the full range of cannabinoids, and motives for use specifically in pregnant women. Taken together, our review reveals the need to continue to improve upon study designs in order to allow researchers to accurately draw conclusions about the development of behavioral consequences of prenatal cannabis exposure. Findings from such studies would inform policy and practices regarding cannabis use during pregnancy and move the field toward developing a comprehensive teratogenic profile of cannabis similar to what is characterized in the prenatal alcohol and tobacco literature.

Indexed as

adolescenceexternalizing traitsprenatal cannabis exposuresubstance use

Identifiers

PMID35051059
PMCPMC8779620
OpenAlexW4206521615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.