Evidence map›Paper›PMID 35051034›Full record

ArticleToxins2022

Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion

Jonas Krämer, Tim Lüddecke, Michael Marner, Elena Maiworm, Johanna Eichberg, Kornelia Hardes, Till F Schäberle, Andreas Vilcinskas, Reinhard Predel

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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  14. International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jonas KrämerInstitute of Zoology, University of Cologne, Zuelpicher Strasse 47b, 50674 Cologne, Germany.
Tim LüddeckeDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.
Michael MarnerDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.ORCID 0000-0002-1024-1567
Elena MaiwormDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.
Johanna EichbergDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.
Kornelia HardesDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.
Till F SchäberleDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.ORCID 0000-0001-9947-8079
Andreas VilcinskasDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Ohlebergsweg 12, 35392 Giessen, Germany.ORCID 0000-0001-8276-4968
Reinhard PredelInstitute of Zoology, University of Cologne, Zuelpicher Strasse 47b, 50674 Cologne, Germany.
Fraunhofer Institute for Molecular Biology and Applied Ecology · DEJustus-Liebig-Universität Gießen · DELOEWE Centre for Translational Biodiversity Genomics · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linear cationic venom peptides are antimicrobial peptides (AMPs) that exert their effects by damaging cell membranes. These peptides can be highly specific, and for some, a significant therapeutic value was proposed, in particular for treatment of bacterial infections. A prolific source of novel AMPs are arthropod venoms, especially those of hitherto neglected groups such as pseudoscorpions. In this study, we describe for the first time pharmacological effects of AMPs discovered in pseudoscorpion venom. We examined the antimicrobial, cytotoxic, and insecticidal activity of full-length Checacin1, a major component of the

Indexed as

Anti-Infective AgentsArthropod ProteinsArthropod VenomsCytotoxinsInsecticidesAmino Acid SequenceAnimalsAphidsArachnidaDogsMadin Darby Canine Kidney CellsSequence AlignmentAnti-Infective AgentsArthropod ProteinsArthropod VenomsCytotoxinsInsecticidesantimicrobial activityantimicrobial peptideschecacincytotoxic activityinsecticidal activitymegicinpseudoscorpion venom

Identifiers

PMID35051034
PMCPMC8778599
OpenAlexW4205815303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.