Evidence map›Paper›PMID 35050571›Full record

ArticleAnalytical chemistry2022

Application of a Target-Guided Data Processing Approach in Saturated Peak Correction of GC×GC Analysis.

Penghan Zhang, Silvia Carlin, Pietro Franceschi, Fulvio Mattivi, Urska Vrhovsek

Abstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Flint glass bottles cause white wine aroma identity degradation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Penghan ZhangResearch and Innovation Center, Edmund Mach Foundation, Via E. Mach 1, San Michele all'Adige 38098, Italy.ORCID 0000-0001-8445-9107
Silvia CarlinResearch and Innovation Center, Edmund Mach Foundation, Via E. Mach 1, San Michele all'Adige 38098, Italy.
Pietro FranceschiResearch and Innovation Center, Edmund Mach Foundation, Via E. Mach 1, San Michele all'Adige 38098, Italy.ORCID 0000-0001-5711-4429
Fulvio MattiviResearch and Innovation Center, Edmund Mach Foundation, Via E. Mach 1, San Michele all'Adige 38098, Italy.
Urska VrhovsekResearch and Innovation Center, Edmund Mach Foundation, Via E. Mach 1, San Michele all'Adige 38098, Italy.ORCID 0000-0002-7921-3249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detector and column saturations are problematic in comprehensive two-dimensional gas chromatography (GC×GC) data analysis. This limits the application of GC×GC in metabolomics research. To address the problems caused by detector and column saturations, we propose a two-stage data processing strategy that will incorporate a targeted data processing and cleaning approach upstream of the "standard" untargeted analysis. By using the retention time and mass spectrometry (MS) data stored in a library, the annotation and quantification of the targeted saturated peaks have been significantly improved. After subtracting the nonperfected signals caused by saturation, peaks of coelutes can be annotated more accurately. Our research shows that the target-guided method has broad application prospects in the data analysis of GC×GC chromatograms of complex samples.

Indexed as

MetabolomicsChemical PhenomenaGas Chromatography-Mass SpectrometryPhysical Phenomena

Identifiers

PMID35050571
PMCPMC8811747

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.