Evidence map›Paper›PMID 35050443›Full record

ArticleBiomolecular NMR assignments2022

Assignment of Ala, Ile, Leu

Thorben Maass, Leon Torben Westermann, Robert Creutznacher, Alvaro Mallagaray, Jasmin Dülfer, Charlotte Uetrecht, Thomas Peters

Abstract read
In one paragraph

Article in Biomolecular NMR assignments, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. AMIGO - Guided assignment ofJournal of biomolecular NMR · 2026
    Article
  2. Virus-Glycan Interactions Studied by Solute NMR.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thorben MaassCenter of Structural and Cell Biology in Medicine (CSCM), Institute of Chemistry and Metabolomics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Leon Torben WestermannCenter of Structural and Cell Biology in Medicine (CSCM), Institute of Chemistry and Metabolomics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Robert CreutznacherCenter of Structural and Cell Biology in Medicine (CSCM), Institute of Chemistry and Metabolomics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Alvaro MallagarayCenter of Structural and Cell Biology in Medicine (CSCM), Institute of Chemistry and Metabolomics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Jasmin DülferLeibniz Institute for Experimental Virology (HPI), 20251, Hamburg, Germany.
Charlotte UetrechtLeibniz Institute for Experimental Virology (HPI), 20251, Hamburg, Germany.
Thomas PetersCenter of Structural and Cell Biology in Medicine (CSCM), Institute of Chemistry and Metabolomics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany. thomas.peters@uni-luebeck.de.ORCID 0000-0002-7570-8260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protruding domain (P-domain) of the murine norovirus (MNV) capsid protein VP1 is essential for infection. It mediates receptor binding and attachment of neutralizing antibodies. Protein NMR studies into interactions of the P-domain with ligands will yield insights not easily available from other biophysical techniques and will extend our understanding of MNV attachment to host cells. Such studies require at least partial NMR assignments. Here, we describe the assignment of about 70% of the Ala, Ile, Leu

Indexed as

NorovirusAnimalsCapsid ProteinsMiceMutagenesis, Site-DirectedNuclear Magnetic Resonance, BiomolecularProtein BindingCapsid Proteins4D HMQC-NOESY-HMQCMass spectrometryMethyl group assignmentNorovirusP-domainPeptide mappingProline cis/transPseudo contact shifts

Identifiers

PMID35050443
PMCPMC9068638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.