Evidence map›Paper›PMID 35050237›Full record

ArticleJournal of cardiovascular development and disease2022

Cardiopulmonary Exercise Testing in Repaired Tetralogy of Fallot: Multiparametric Overview and Correlation with Cardiac Magnetic Resonance and Physical Activity Level.

Benedetta Leonardi, Federica Gentili, Marco Alfonso Perrone, Fabrizio Sollazzo, Lucia Cocomello, Stefani Silva Kikina, Rachel M Wald, Vincenzo Palmieri, Aurelio Secinaro, Maria Giulia Gagliardi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Guideline
  2. A modelling study of right ventricular growth with valvular regurgitation.Biomechanics and modeling in mechanobiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. The association between OInternational journal of cardiology. Heart & vasculature · 2024
    Article
  10. Article
  11. Tetralogy of Fallot Across the Lifespan: A Focus on the Right Ventricle.CJC pediatric and congenital heart disease · 2023
    Review
  12. Physical Activity Promotion Among Individuals With Tetralogy of Fallot.CJC pediatric and congenital heart disease · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Pediatric Myocarditis: What Have We Learnt So Far?Journal of cardiovascular development and disease · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Benedetta LeonardiDepartment of Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Federica GentiliDepartment of Sport Medicine, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Marco Alfonso PerroneDepartment of Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Fabrizio SollazzoUnità Operativa Complessa di Medicina dello Sport e Rieducazione Funzionale, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Lucia CocomelloBristol Heart Institute, University of Bristol, Bristol BS2 8HW, UK.ORCID 0000-0002-9967-1861
Stefani Silva KikinaUnità Operativa Complessa di Medicina dello Sport e Rieducazione Funzionale, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0003-3228-3773
Rachel M WaldPeter Munk Cardiac Centre and Joint Department of Medical Imaging, University Health Network, University of Toronto, Toronto, ON M5S 1A1, Canada.
Vincenzo PalmieriUnità Operativa Complessa di Medicina dello Sport e Rieducazione Funzionale, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Aurelio SecinaroAdvanced Cardiothoracic Imaging Unit, Department of Imaging, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Maria Giulia GagliardiDepartment of Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Attilio ParisiDepartment of Movement, Human and Health Science, University of Rome Foro Italico, 00135 Rome, Italy.
Attilio TurchettaDepartment of Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Lorenzo GallettiDepartment of Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Massimiliano BiancoUnità Operativa Complessa di Medicina dello Sport e Rieducazione Funzionale, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-0587-5899
Fabrizio DragoDepartment of Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.ORCID 0000-0003-1888-373X
Bambino Gesù Children's Hospital · ITUniversità Cattolica del Sacro Cuore · ITForo Italico University of Rome · ITUniversity Health Network · CAUniversity of Bristol · GBUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with repaired Tetralogy of Fallot (rToF) typically report having preserved subjective exercise tolerance. Chronic pulmonary regurgitation (PR) with varying degrees of right ventricular (RV) dilation as assessed by cardiac magnetic resonance imaging (MRI) is prevalent in rToF and may contribute to clinical compromise. Cardiopulmonary exercise testing (CPET) provides an objective assessment of functional capacity, and the International Physical Activity Questionnaire (IPAQ) can provide additional data on physical activity (PA) achieved. Our aim was to assess the association between CPET values, IPAQ measures, and MRI parameters. All rToF patients who had both an MRI and CPET performed within one year between March 2019 and June 2021 were selected. Clinical data were extracted from electronic records (including demographic, surgical history, New York Heart Association (NYHA) functional class, QRS duration, arrhythmia, MRI parameters, and CPET data). PA level, based on the IPAQ, was assessed at the time of CPET. Eighty-four patients (22.8 ± 8.4 years) showed a reduction in exercise capacity (median peak VO

Indexed as

cardiac magnetic resonancecardiopulmonary exercise testingexercise capacityphysical activitypulmonary valvetetralogy of Fallot

Identifiers

PMID35050237
PMCPMC8778451
OpenAlexW4206014321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.