Evidence map›Paper›PMID 35050221›Full record

ArticleJournal of cardiovascular development and disease2022

Electrocardiographic Characteristics and Their Correlation with Echocardiographic Alterations in Fabry Disease.

Matthew Zada, Queenie Lo, Siddharth J Trivedi, Mehmet Harapoz, Anita C Boyd, Kerry Devine, Norman Sadick, Michel C Tchan, Liza Thomas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Fabry disease caused by theMolecular genetics and metabolism reports · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Matthew ZadaWestmead Clinical School, Westmead Hospital, University of Sydney, Sydney 2145, Australia.ORCID 0000-0003-3934-687X
Queenie LoSouth Western Sydney Clinical School, Liverpool Hospital, University of New South Wales, Sydney 1466, Australia.
Siddharth J TrivediWestmead Clinical School, Westmead Hospital, University of Sydney, Sydney 2145, Australia.
Mehmet HarapozWestmead Clinical School, Westmead Hospital, University of Sydney, Sydney 2145, Australia.ORCID 0000-0001-8537-9723
Anita C BoydWestmead Private Cardiology, Sydney 2145, Australia.
Kerry DevineGenetic Medicine, Westmead Hospital, Sydney 2145, Australia.
Norman SadickWestmead Clinical School, Westmead Hospital, University of Sydney, Sydney 2145, Australia.
Michel C TchanGenetic Medicine, Westmead Hospital, Sydney 2145, Australia.ORCID 0000-0001-9700-7898
Liza ThomasWestmead Clinical School, Westmead Hospital, University of Sydney, Sydney 2145, Australia.
The University of Sydney · AUWestmead Hospital · AULiverpool Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fabry disease (FD) is an X-linked disorder with α-galactosidase A deficiency. Males (>30 years) and females (>40 years) often present with cardiac manifestations, predominantly left ventricular hypertrophy (LVH). The aim of this study was to evaluate electrocardiographic (ECG) characteristics within FD patients to identify gender related differences, and to additionally explore the association of ECG parameters with structural and functional alterations on transthoracic echocardiography (TTE). Retrospective cross-sectional analysis of 45 FD patients with contemporaneous ECG and TTE was performed and compared to age and gender matched healthy controls. FD patients demonstrated alterations in several ECG parameters particularly in males, including prolonged P-wave duration (91 vs. 81 ms,

Indexed as

basal longitudinal strainelectrocardiogramFabry diseaseglobal longitudinal strainLV hypertrophytransthoracic echocardiography

Identifiers

PMID35050221
PMCPMC8777656
OpenAlexW4205671839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.