Evidence map›Paper›PMID 35050178›Full record

ArticleMetabolites2022

Metabolomic Analysis of Carbohydrate and Amino Acid Changes Induced by Hypoxia in Naked Mole-Rat Brain and Liver.

Hang Cheng, Yiming Amy Qin, Rashpal Dhillon, James Dowell, John M Denu, Matthew E Pamenter

Abstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Nonpolysaccharide fraction ofFrontiers in pharmacology · 2026
    Article
  3. Article
  4. CaCellular and molecular neurobiology · 2025
    Article
  5. Article
  6. Article
  7. Metabolic stability of the Pallas' spadefoot Pelobates vespertinus under extreme hypoxia.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Article
  8. Neural Processing without OPhysiology (Bethesda, Md.) · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hang ChengBiology Department, University of Ottawa, Ottawa, ON K1N 6N5, Canada.ORCID 0000-0002-5251-640X
Yiming Amy QinDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Rashpal DhillonWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53706, USA.
James DowellWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53706, USA.
John M DenuDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Matthew E PamenterBiology Department, University of Ottawa, Ottawa, ON K1N 6N5, Canada.ORCID 0000-0003-4035-9555

Funding

Molecular mechanisms of histone modification - Alzheimer’s supplement NOT-AG-18-008R37GM059785 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI DENU, JOHN M · 2013 to 2022
$3.7M
Molecular Mechanisms of Histone AcetyltransferasesR01GM059785 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI DENU, JOHN M · 1999 to 2012
$2.9M
Canada Research Chairs 950-230954Natural Sciences and Engineering Research Council 04229NIGMS NIH HHS GM059785
6 · The paper itself

Abstract

Hypoxia poses a major physiological challenge for mammals and has significant impacts on cellular and systemic metabolism. As with many other small rodents, naked mole-rats (NMRs;

Indexed as

AMPaspartic acidcoenzymedopamineglutamateglutamineglutathioneglycogenpentose phosphate pathway

Identifiers

PMID35050178
PMCPMC8779284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.