Evidence map›Paper›PMID 35050174›Full record

ReviewMetabolites2022

Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review.

Vanessa Neto, Sara Esteves-Ferreira, Isabel Inácio, Márcia Alves, Rosa Dantas, Idália Almeida, Joana Guimarães, Teresa Azevedo, Alexandra Nunes

Abstract readReview
In one paragraph

Review in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vanessa NetoDepartment of Medical Sciences, iBiMED-Institute of Biomedicine, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-9703-8667
Sara Esteves-FerreiraCentro Hospitalar do Baixo Vouga, CHBV-Endocrinology Department, 3810-164 Aveiro, Portugal.ORCID 0000-0003-4412-4913
Isabel InácioCentro Hospitalar do Baixo Vouga, CHBV-Endocrinology Department, 3810-164 Aveiro, Portugal.ORCID 0000-0002-5777-5136
Márcia AlvesCentro Hospitalar do Baixo Vouga, CHBV-Endocrinology Department, 3810-164 Aveiro, Portugal.
Rosa DantasCentro Hospitalar do Baixo Vouga, CHBV-Endocrinology Department, 3810-164 Aveiro, Portugal.ORCID 0000-0002-1666-0922
Idália AlmeidaDepartment of Medical Sciences, iBiMED-Institute of Biomedicine, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-0639-0666
Joana GuimarãesCentro Hospitalar do Baixo Vouga, CHBV-Endocrinology Department, 3810-164 Aveiro, Portugal.
Teresa AzevedoCentro Hospitalar do Baixo Vouga, CHBV-Endocrinology Department, 3810-164 Aveiro, Portugal.
Alexandra NunesDepartment of Medical Sciences, iBiMED-Institute of Biomedicine, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-0595-5821

Funding

Compete2020 and FEDER CENTRO-01-0246-FEDER-000018Fundação para a Ciência e Tecnologia UIDB/04501/2020 and POCI-01-0145-FEDER-007628
6 · The paper itself

Abstract

Thyroid cancer's incidence has increased in the last decades, and its diagnosis can be a challenge. Further and complementary testing based in biochemical alterations may be important to correctly identify thyroid cancer and prevent unnecessary surgery. Fourier-transform infrared (FTIR) spectroscopy is a metabolomic technique that has already shown promising results in cancer metabolome analysis of neoplastic thyroid tissue, in the identification and classification of prostate tumor tissues and of breast carcinoma, among others. This work aims to gather and discuss published information on the ability of FTIR spectroscopy to be used in metabolomic studies of the thyroid, including discriminating between benign and malignant thyroid samples and grading and classifying different types of thyroid tumors.

Indexed as

Fourier-transform infrared spectroscopymetabolomemultivariate analysisnodular thyroid pathologythyroid cancerthyroid cytologythyroid tissue

Identifiers

PMID35050174
PMCPMC8777789

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.