ReviewMetabolites2021
Defining Blood Plasma and Serum Metabolome by GC-MS.
Review in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets.Journal of proteome research · 2024Trial
- PMconv: How to Compare Proteomes and Metabolomes?International journal of molecular sciences · 2026Article
- Metabolomic responses are more sensitive in muscle than serum following 28 days of arduous exercise with erythropoietin administration.Experimental physiology · 2026Article
- Exhaled Breath Analysis for Head and Neck Cancer Using Fourier-Transform Infrared Spectroscopy: A Feasibility Study for Non-Invasive Screening.Diagnostics (Basel, Switzerland) · 2026Article
- Elemental and biomolecular changes in serum as indicators of SPION action in the body: analysis using TXRF, FTIR and Raman spectroscopy.Scientific reports · 2025Article
- The Utility of Metabolomics in Spinal Cord Injury: Opportunities for Biomarker Discovery and Neuroprotection.International journal of molecular sciences · 2025Review
- Association of metabolic dysregulation with treatment response in rectal cancer patients undergoing chemoradiotherapy.BMC medical genomics · 2025Article
- Examination of Intermolecular Forces Influencing Headspace Analysis of Biological Samples.Metabolites · 2025Article
- Development and Validation of Targeted Metabolomics Methods Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) for the Quantification of 235 Plasma Metabolites.Molecules (Basel, Switzerland) · 2025Article
- Integrating metabolomics for precision nutrition in poultry: optimizing growth, feed efficiency, and health.Frontiers in veterinary science · 2025Review
- Metabolic perturbations in cardiomyopathies: implications for early diagnosis and targeted interventions.Frontiers in cardiovascular medicine · 2025Review
- Impact of Metabolites from Foodborne Pathogens on Cancer.Foods (Basel, Switzerland) · 2024Review
- Precision Medicine for Cardiovascular Prevention and Population Health: A Bridge Too Far?Circulation · 2024Review
- Serum and Urine Metabolites and Kidney Function.Journal of the American Society of Nephrology : JASN · 2024Article
- Serum-volatile organic compounds in the diagnostics of esophageal cancer.Scientific reports · 2024Article
- Alterations in metabolome and lipidome in patients with in-stent restenosis.CNS neuroscience & therapeutics · 2024Article
- Revealing novel biomarkers for diagnosing chronic kidney disease in pediatric patients.Scientific reports · 2024Article
- Gut microbiota-derived cholic acid mediates neonatal brain immaturity and white matter injury under chronic hypoxia.iScience · 2024Article
- Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication.iScience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Metabolomics uses advanced analytical chemistry methods to analyze metabolites in biological samples. The most intensively studied samples are blood and its liquid components: plasma and serum. Armed with advanced equipment and progressive software solutions, the scientific community has shown that small molecules' roles in living systems are not limited to traditional "building blocks" or "just fuel" for cellular energy. As a result, the conclusions based on studying the metabolome are finding practical reflection in molecular medicine and a better understanding of fundamental biochemical processes in living systems. This review is not a detailed protocol of metabolomic analysis. However, it should support the reader with information about the achievements in the whole process of metabolic exploration of human plasma and serum using mass spectrometry combined with gas chromatography.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.