Evidence map›Paper›PMID 35049968›Full record

ReviewJournal of fungi (Basel, Switzerland)2021

Recent Developments in Metabolomics Studies of Endophytic Fungi.

Kashvintha Nagarajan, Baharudin Ibrahim, Abdulkader Ahmad Bawadikji, Jun-Wei Lim, Woei-Yenn Tong, Chean-Ring Leong, Kooi Yeong Khaw, Wen-Nee Tan

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Incorporating omics-based tools into endophytic fungal research.Biotechnology notes (Amsterdam, Netherlands) · 2024
    Review
  10. Diversity and Advantages of Culturable Endophytic Fungi from Tea (Journal of fungi (Basel, Switzerland) · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Metabolomics Analysis and Antioxidant Potential of EndophyticJournal of fungi (Basel, Switzerland) · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kashvintha NagarajanChemistry Section, School of Distance Education, Universiti Sains Malaysia, Penang 11800, Malaysia.
Baharudin IbrahimSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0001-8534-2517
Abdulkader Ahmad BawadikjiSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0003-2986-2977
Jun-Wei LimDepartment of Fundamental and Applied Sciences, HICoE-Centre for Biofuel and Biochemical Research, Institute of Self-Sustainable Building, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, Malaysia.ORCID 0000-0003-0158-8822
Woei-Yenn TongDrug Discovery and Delivery Research Laboratory, Malaysian Institute of Chemical and Bioengineering Technology, Universiti Kuala Lumpur, Alor Gajah, Melaka 78000, Malaysia.
Chean-Ring LeongDrug Discovery and Delivery Research Laboratory, Malaysian Institute of Chemical and Bioengineering Technology, Universiti Kuala Lumpur, Alor Gajah, Melaka 78000, Malaysia.
Kooi Yeong KhawSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Malaysia.ORCID 0000-0003-2360-6235
Wen-Nee TanChemistry Section, School of Distance Education, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0002-7812-3946

Funding

Ministry of Higher Education Malaysia for Fundamental Research Grant Scheme FRGS/1/2018/STG01/USM/02/3
6 · The paper itself

Abstract

Endophytic fungi are microorganisms that colonize living plants' tissues without causing any harm. They are known as a natural source of bioactive metabolites with diverse pharmacological functions. Many structurally different chemical metabolites were isolated from endophytic fungi. Recently, the increasing trends in human health problems and diseases have escalated the search for bioactive metabolites from endophytic fungi. The conventional bioassay-guided study is known as laborious due to chemical complexity. Thus, metabolomics studies have attracted extensive research interest owing to their potential in dealing with a vast number of metabolites. Metabolomics coupled with advanced analytical tools provides a comprehensive insight into systems biology. Despite its wide scientific attention, endophytic fungi metabolomics are relatively unexploited. This review highlights the recent developments in metabolomics studies of endophytic fungi in obtaining the global metabolites picture.

Indexed as

analytical toolbioactive metabolitesendophytic fungiextractionliquid chromatography–high-resolution mass spectrometrymetabolomicsnuclear magnetic resonancesystems biology

Identifiers

PMID35049968
PMCPMC8781825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.