Evidence map›Paper›PMID 35049961›Full record

ReviewJournal of fungi (Basel, Switzerland)2021

Biosynthesis Pathways, Transport Mechanisms and Biotechnological Applications of Fungal Siderophores.

Lorenzo Pecoraro, Xiao Wang, Dawood Shah, Xiaoxuan Song, Vishal Kumar, Abdul Shakoor, Keshawanand Tripathi, Pramod W Ramteke, Rupa Rani

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. BiofortifiedMolecules (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Plant Growth-Promoting Yeasts fromJournal of agricultural and food chemistry · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Targeting Siderophore Biosynthesis to Thwart Microbial Growth.International journal of molecular sciences · 2025
    Review
  18. Article
  19. Review
  20. JACS Au · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Lorenzo PecoraroSchool of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China.ORCID 0000-0002-3234-4698
Xiao WangSchool of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China.ORCID 0000-0001-5028-3668
Dawood ShahSchool of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China.
Xiaoxuan SongSchool of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China.
Vishal KumarDepartment of Food Science and Technology, Yeungnam University, Gyongsan 38541, Korea.
Abdul ShakoorSchool of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China.
Keshawanand TripathiCenter for Conservation and Utilization of Blue-Green Algae, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India.ORCID 0000-0002-2106-5896
Pramod W RamtekeFaculty of Life Sciences, Mandsaur University, Mandsaur 458001, India.
Rupa RaniSchool of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China.ORCID 0000-0002-3727-7172
Tianjin University · CNIndian Agricultural Research Institute · INYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron (Fe) is the fourth most abundant element on earth and represents an essential nutrient for life. As a fundamental mineral element for cell growth and development, iron is available for uptake as ferric ions, which are usually oxidized into complex oxyhydroxide polymers, insoluble under aerobic conditions. In these conditions, the bioavailability of iron is dramatically reduced. As a result, microorganisms face problems of iron acquisition, especially under low concentrations of this element. However, some microbes have evolved mechanisms for obtaining ferric irons from the extracellular medium or environment by forming small molecules often regarded as siderophores. Siderophores are high affinity iron-binding molecules produced by a repertoire of proteins found in the cytoplasm of cyanobacteria, bacteria, fungi, and plants. Common groups of siderophores include hydroxamates, catecholates, carboxylates, and hydroximates. The hydroxamate siderophores are commonly synthesized by fungi. L-ornithine is a biosynthetic precursor of siderophores, which is synthesized from multimodular large enzyme complexes through non-ribosomal peptide synthetases (NRPSs), while siderophore-Fe chelators cell wall mannoproteins (FIT1, FIT2, and FIT3) help the retention of siderophores.

Indexed as

biocontrolbioremediationbiotechnologyfungal cytoplasm proteinshydroxamateiron-binding moleculesiron uptakemedicinesiderophore biosynthesissiderophore-Fe chelators mannoproteins

Identifiers

PMID35049961
PMCPMC8781417
OpenAlexW4200345036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.