Evidence map›Paper›PMID 35049933›Full record

ArticleMarine drugs2022

Isoquinoline Alkaloids as Protein Tyrosine Phosphatase Inhibitors from a Deep-Sea-Derived Fungus

Cheng-Mei Liu, Fei-Hua Yao, Xin-Hua Lu, Xue-Xia Zhang, Lian-Xiang Luo, Xiao Liang, Shu-Hua Qi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cheng-Mei LiuCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Fei-Hua YaoCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Xin-Hua LuNew Drug Research & Development Co., Ltd., North China Pharmaceutical Group Corporation, Shijiazhuang 050015, China.
Xue-Xia ZhangNew Drug Research & Development Co., Ltd., North China Pharmaceutical Group Corporation, Shijiazhuang 050015, China.
Lian-Xiang LuoThe Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang 524023, China.ORCID 0000-0002-3391-9713
Xiao LiangCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Shu-Hua QiCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.

Funding

Guangdong Provincial-level Special Funds for Promoting High-quality Economic Development 2020032Institution of South China Sea Ecology and Environmental Engineering ISEE2021PY05Key-Area Research and Development Program of Guangdong Province 2020B1111030005Key Science and Technology Project of Hainan Province ZDKJ202018Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) GML2019ZD0406National Natural Science Foundation of China 82173709
6 · The paper itself

Abstract

Puniceusines A-N (

Indexed as

AspergillusAlkaloidsAnimalsAnti-Bacterial AgentsAntineoplastic AgentsAquatic OrganismsCell Line, TumorHumansInhibitory Concentration 50IsoquinolinesMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsProtein Tyrosine PhosphatasesAlkaloidsAnti-Bacterial AgentsAntineoplastic AgentsisoquinolineIsoquinolinesProtein Tyrosine PhosphatasesantibacterialAspergillus puniceuscytotoxicitydeep-sea-derived fungusisoquinoline alkaloidprotein tyrosine phosphatase inhibitor

Identifiers

PMID35049933
PMCPMC8781450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.