Evidence map›Paper›PMID 35049922›Full record

ReviewMarine drugs2022

Secondary Metabolites from Marine-Derived Fungi and Actinobacteria as Potential Sources of Novel Colorectal Cancer Drugs.

Elin Julianti, Ikram Ammar Abrian, Marlia Singgih Wibowo, Muhammad Azhari, Nadya Tsurayya, Fauzia Izzati, Ario Betha Juanssilfero, Asep Bayu, Siti Irma Rahmawati, Masteria Yunovilsa Putra

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Isolation of a novel marineJournal of biosciences · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. MarineMarine drugs · 2023
    Review
  9. Thiolactones and ΔMarine drugs · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Mushrooms as future generation healthy foods.Frontiers in nutrition · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Elin JuliantiSchool of Pharmacy, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132, Indonesia.
Ikram Ammar AbrianSchool of Pharmacy, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132, Indonesia.
Marlia Singgih WibowoSchool of Pharmacy, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132, Indonesia.
Muhammad AzhariSchool of Pharmacy, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132, Indonesia.ORCID 0000-0003-3966-582X
Nadya TsurayyaSchool of Pharmacy, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132, Indonesia.ORCID 0000-0002-7159-5748
Fauzia IzzatiResearch Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor 16911, Indonesia.ORCID 0000-0003-1613-3070
Ario Betha JuanssilferoResearch Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor 16911, Indonesia.
Asep BayuResearch Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor 16911, Indonesia.
Siti Irma RahmawatiResearch Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor 16911, Indonesia.
Masteria Yunovilsa PutraResearch Center for Biotechnology, Research Organization for Life Sciences, National Research and Innovation Agency (BRIN), Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor 16911, Indonesia.ORCID 0000-0002-9879-3293
Bandung Institute of Technology · IDNational Research and Innovation Agency · ID

Funding

Ministry of Research, Technology and Higher Education WCP 2021
6 · The paper itself

Abstract

Colorectal cancer is one of the most common cancers diagnosed in the world. Chemotheraphy is one of the most common methods used for the pharmacological treatment of this cancer patients. Nevertheless, the adverse effect of chemotherapy is not optimized for improving the quality of life of people who are older, who are the most vulnerable subpopulation. This review presents recent updates regarding secondary metabolites derived from marine fungi and actinobacteria as novel alternatives for cytotoxic agents against colorectal cancer cell lines HCT116, HT29, HCT15, RKO, Caco-2, and SW480. The observed marine-derived fungi were from the species

Indexed as

ActinobacteriaFungiAnimalsAntineoplastic AgentsAquatic OrganismsCaco-2 CellsColorectal NeoplasmsDiketopiperazinesHCT116 CellsHumansIndole AlkaloidsAntineoplastic AgentsDiketopiperazinesIndole Alkaloidsactinobacteriacolorectal cancercytotoxicityfungimarinesecondary metabolite

Identifiers

PMID35049922
PMCPMC8777761
OpenAlexW4206791646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.