Evidence map›Paper›PMID 35049921›Full record

ArticleMarine drugs2022

Cloning and Characterization of a Novel Alginate Lyase from

Mingpeng Wang, Lei Chen, Zhengyu Lou, Xueting Yuan, Guiping Pan, Xiaoyan Ren, Pengyu Wang

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mingpeng WangCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Lei ChenCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Zhengyu LouCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Xueting YuanCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Guiping PanCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Xiaoyan RenCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Pengyu WangCollege of Life Science, Qufu Normal University, Qufu 273100, China.
Qufu Normal University · CN

Funding

Natural Science Foundation of Shandong Province ZR2019QB018the Young Scientists Fund of National Natural Science Foundation of China 41401285
6 · The paper itself

Abstract

As a low molecular weight alginate, alginate oligosaccharides (AOS) exhibit improved water solubility, better bioavailability, and comprehensive health benefits. In addition, their biocompatibility, biodegradability, non-toxicity, non-immunogenicity, and gelling capability make them an excellent biomaterial with a dual curative effect when applied in a drug delivery system. In this paper, a novel alginate lyase, Algpt, was cloned and characterized from a marine bacterium,

Indexed as

AlginatesAnimalsAquatic OrganismsChinaCloning, MolecularDrug Delivery SystemsLyasesPaenibacillusAlginatesLyasesalginate degradationalginate lyasealginate oligosaccharidesdrug deliveryPaenibacillus

Identifiers

PMID35049921
PMCPMC8780880
OpenAlexW4206021984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.