Evidence map›Paper›PMID 35049920›Full record

ArticleMarine drugs2022

Insights into Cytotoxic Behavior of Lepadins and Structure Elucidation of the New Alkaloid Lepadin L from the Mediterranean Ascidian

Marcello Casertano, Massimo Genovese, Paolo Paoli, Alice Santi, Anna Aiello, Marialuisa Menna, Concetta Imperatore

Abstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Azine Dearomatization in Natural Product Total Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcello CasertanoDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0001-5037-712X
Massimo GenoveseDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Paolo PaoliDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.ORCID 0000-0001-6448-7266
Alice SantiDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Anna AielloDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.
Marialuisa MennaDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-4515-3014
Concetta ImperatoreDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0001-7377-0653

Funding

Dipartimento di Farmacia, Università di Napoli Federico II Bando contributo alla ricerca- Anno 2021Regione Campania B61G18000470007
6 · The paper itself

Abstract

The chemical investigation of the Mediterranean ascidian

Indexed as

UrochordataAlkaloidsAnimalsAntineoplastic AgentsAquatic OrganismsCell Line, TumorHumansMediterranean SeaMiceStructure-Activity RelationshipAlkaloidsAntineoplastic AgentsascidiansClavelina lepadiformiscytotoxic activitydecahydroquinoline-based alkaloidsmarine natural productsstructural determination

Identifiers

PMID35049920
PMCPMC8782007

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.