Unveiling the Chemical Diversity of the Deep-Sea Sponge

Sam Afoullouss, Anthony R Sanchez, Laurence K Jennings, Younghoon Kee, A Louise Allcock, Olivier P Thomas

Open access · goldAbstract read

In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.6field-weighted citation impact, top 37% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

New insights into the microbiome of the deep-sea spongeMicrobial genomics · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sam AfoulloussMarine Biodiscovery, School of Chemistry and Ryan Institute, National University of Ireland Galway (NUI Galway), University Road, H91TK33 Galway, Ireland.ORCID 0000-0003-0479-8032

Anthony R SanchezDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620, USA.ORCID 0000-0002-9353-6220

Laurence K JenningsMarine Biodiscovery, School of Chemistry and Ryan Institute, National University of Ireland Galway (NUI Galway), University Road, H91TK33 Galway, Ireland.ORCID 0000-0002-1313-0360

Younghoon KeeDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620, USA.

A Louise AllcockSchool of Natural Sciences and Ryan Institute, National University of Ireland Galway (NUI Galway), University Road, H91TK33 Galway, Ireland.ORCID 0000-0002-4806-0040

Olivier P ThomasMarine Biodiscovery, School of Chemistry and Ryan Institute, National University of Ireland Galway (NUI Galway), University Road, H91TK33 Galway, Ireland.ORCID 0000-0002-5708-1409

Ollscoil na Gaillimhe – University of Galway · IEUniversity of South Florida · US

Funding

Science Foundation Ireland SFI/15/1A/3100

6 · The paper itself

Abstract

Sponges are at the forefront of marine natural product research. In the deep sea, extreme conditions have driven secondary metabolite pathway evolution such that we might expect deep-sea sponges to yield a broad range of unique natural products. Here, we investigate the chemodiversity of a deep-sea tetractinellid sponge,

Indexed as

PoriferaAnimalsAntineoplastic AgentsAquatic OrganismsFemaleHeLa CellsHumansUterine Cervical NeoplasmsVitamin B 12Antineoplastic AgentsVitamin B 12Characellacyanocobalamindeep-seahercyninemolecular networkingpoecillastrinssponge

Identifiers

PMID35049906

DOI10.3390/md20010052

PMCPMC8779493

OpenAlexW4206293549

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.