Evidence map›Paper›PMID 35049898›Full record

ArticleMarine drugs2022

Bacillimidazoles A-F, Imidazolium-Containing Compounds Isolated from a Marine

Jia-Xuan Yan, Qihao Wu, Eric J N Helfrich, Marc G Chevrette, Doug R Braun, Heino Heyman, Gene E Ananiev, Scott R Rajski, Cameron R Currie, Jon Clardy and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jia-Xuan YanPharmaceutical Sciences Division, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA.
Qihao WuPharmaceutical Sciences Division, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA.
Eric J N HelfrichHarvard Medical School, Harvard University, 240 Longwood Ave, Boston, MA 02115, USA.
Marc G ChevretteDepartment of Bacteriology, University of Wisconsin-Madison, 1550 Linden Ave, Madison, WI 53706, USA.ORCID 0000-0002-7209-0717
Doug R BraunPharmaceutical Sciences Division, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA.
Heino HeymanBruker Daltonics, Bruker Scientific LLC., 40 Manning Rd, Billerica, MA 01821, USA.
Gene E AnanievThe Small Molecule Screening Facility (SMSF), University of Wisconsin-Madison, 600 Highland Ave, Madison, WI 53792, USA.
Scott R RajskiPharmaceutical Sciences Division, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA.ORCID 0000-0002-0238-8411
Cameron R CurrieDepartment of Bacteriology, University of Wisconsin-Madison, 1550 Linden Ave, Madison, WI 53706, USA.
Jon ClardyHarvard Medical School, Harvard University, 240 Longwood Ave, Boston, MA 02115, USA.
Tim S BugniPharmaceutical Sciences Division, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA.ORCID 0000-0002-4502-3084

Funding

Novel antimicrobials targeting MDR pathogens from animal microbial symbiontsU19AI142720 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R · 2019 to 2023
$30.1M
Metabolomics driven discovery of drug leads from symbiotic bacteriaU19AI109673 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R, CURRIE, CAMERON ROBERT · 2014 to 2018
$16.2M
Chemical biology of bacterial symbiontsR01AT009874 · NCCIH · HARVARD MEDICAL SCHOOL · PI CLARDY, JON · 2017 to 2019
$1.2M
National Institute of Health P41GM103399National Institute of Health R01AT009874National Institute of Health RR02781National Institute of Health RR08438National Institute of Health U19AI109673National Science Foundation BIR-9214394National Science Foundation DMB-8415048National Science Foundation OIA-9977484NCCIH NIH HHS R01 AT009874NIAID NIH HHS U19 AI109673NIAID NIH HHS U19 AI142720NIH HHS U19AI141720Swiss National Science Foundation Postdoctoral Mobility FellowshipUnited States Department of Agriculture unknownUniversity of Wisconsin-Madison multiple funds through School of Pharmacy & the Graduate School
6 · The paper itself

Abstract

Chemical investigations of a marine sponge-associated

Indexed as

BacillusPoriferaAnimalsAnti-Bacterial AgentsAquatic OrganismsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsAnti-Bacterial Agentsantibacterialbiosynthetic gene clusterheterocyclesimidazoliumisotopic enrichmentmarine-derived Bacillus

Identifiers

PMID35049898
PMCPMC8779896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.