Evidence map›Paper›PMID 35049893›Full record

ArticleMarine drugs2021

Low Molecular Weight, 4-

Shiwei Hu, Sichun Chen, Hongli Zhu, Mengyu Du, Wei Jiang, Yu Liu, Xiang Gao, Laijin Su, Yangli Xu

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Shiwei HuNational Engineering Research Center for Maine Aquaculture, Zhejiang Ocean University, Zhoushan 316022, China.
Sichun ChenNational Engineering Research Center for Maine Aquaculture, Zhejiang Ocean University, Zhoushan 316022, China.
Hongli ZhuNational Engineering Research Center for Maine Aquaculture, Zhejiang Ocean University, Zhoushan 316022, China.
Mengyu DuNational Engineering Research Center for Maine Aquaculture, Zhejiang Ocean University, Zhoushan 316022, China.
Wei JiangNational Engineering Research Center for Maine Aquaculture, Zhejiang Ocean University, Zhoushan 316022, China.
Yu LiuNational Engineering Research Center for Maine Aquaculture, Zhejiang Ocean University, Zhoushan 316022, China.
Xiang GaoCollege of Life Sciences, Qingdao University, Qingdao 266071, China.
Laijin SuCollege of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.ORCID 0000-0002-5725-2802
Yangli XuWenzhou Characteristic Food Resources Engineering and Technology Research Center, Wenzhou Academy of Agricultural Science, Wenzhou 325006, China.
Zhejiang Ocean University · CNQingdao University · CNWenzhou University · CNWenzhou Vocational College of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fucoidans from sea cucumber (SC-FUC) have been proven to alleviate insulin resistance in several species. However, there are few studies that clarify the relationship between their structure and bioactivity. The present study evaluated the influence of molecular weight (Mw), sulfation concentrations (Cs), and sulfation position on improving insulin resistance using SC-FUC. Results showed that fucoidans with lower Mw exerted stronger effects. Having a similar Mw,

Indexed as

Sea CucumbersAnimalsAquatic OrganismsDiet, High-FatDisease Models, AnimalFucoseHypoglycemic AgentsInsulin ResistanceMaleMiceMice, Inbred C57BLMolecular WeightPolysaccharidesStructure-Activity RelationshipSulfatesfucoidanFucoseHypoglycemic AgentsPolysaccharidesSulfates4-O-sulfationfucoidansinsulin resistancelow molecular weightsea cucumbersulfation at ortho-fucose

Identifiers

PMID35049893
PMCPMC8781073
OpenAlexW4200287518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.