Evidence map›Paper›PMID 35049878›Full record

ArticleMarine drugs2021

Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway.

Ni Pan, Zi-Cheng Li, Zhi-Hong Li, Sen-Hua Chen, Ming-Hua Jiang, Han-Yan Yang, Yao-Sheng Liu, Rui Hu, Yu-Wei Zeng, Le-Hui Dai and 2 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  5. Dihydrogeodin fromMarine drugs · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ni PanDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Zi-Cheng LiDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Zhi-Hong LiDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Sen-Hua ChenSchool of Marine Sciences, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0002-5498-0206
Ming-Hua JiangSchool of Marine Sciences, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0002-3036-3879
Han-Yan YangDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Yao-Sheng LiuDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Rui HuDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Yu-Wei ZengDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Le-Hui DaiDepartment of Basic Medical Sciences, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Lan LiuSchool of Marine Sciences, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0003-2765-4015
Guan-Lei WangDepartment of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Sun Yat-sen University · CN

Funding

National Natural Science Foundation of China 82073848, 81773722, 82104160, 41806155Natural Science Foundation of Guangdong Province 2018A030310304Project supported by Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) SML2021SP319the Science and Technology Program of Guangzhou City 201803010092
6 · The paper itself

Abstract

Isaridin E, a cyclodepsipeptide isolated from the marine-derived fungus

Indexed as

BeauveriaDepsipeptidesFibrinolytic AgentsPlatelet Aggregation InhibitorsAnimalsAquatic OrganismsFungal ProteinsMaleMiceMice, Inbred C57BLPeptides, CyclicPhosphatidylinositol 3-KinasesPlatelet ActivationPlatelet AggregationProto-Oncogene Proteins c-aktSignal TransductionDepsipeptidesFibrinolytic AgentsFungal Proteinsisaridin EPeptides, CyclicPhosphatidylinositol 3-KinasesPlatelet Aggregation InhibitorsProto-Oncogene Proteins c-aktaggregationantithromboticisaridin Emarine fungal natural productsPI3Kplatelets

Identifiers

PMID35049878
PMCPMC8780978
OpenAlexW4200218169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.