ReviewBioengineering (Basel, Switzerland)2022
Speech- and Language-Based Classification of Alzheimer's Disease: A Systematic Review.
Review in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Machine Learning Approaches for Dementia Detection Through Speech and Gait Analysis: A Systematic Literature Review.Journal of Alzheimer's disease : JAD · 2024Pooled it
- Artificial Intelligence for Alzheimer's Disease Diagnosis: From Traditional Machine Learning to Large Language Models.Biosensors · 2026Review
- Enhancing Early Detection of Alzheimer's Disease: An Ensemble Model for Multi-Domain Cognitive Assessment Using Voice and Video.Sensors (Basel, Switzerland) · 2026Article
- Language dysfunction as a primary feature of cognitive decline in neurological populations.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Exploring neural correlates of automated speech-based cognitive markers through resting-state functional connectivity in aging and at-risk Alzheimer's disease.Alzheimer's research & therapy · 2026Article
- Review of Artificial Intelligence for Clinical Use in Alzheimer's Disease and Related Dementias.Seminars in neurology · 2026Review
- Integrating acoustic, prosodic, and phonological features for automatic Alzheimer's detection.Frontiers in aging neuroscience · 2026Article
- The association of common infectious exposures with cognitive performance in community-dwelling older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Alzheimer's disease recognition using graph neural network by leveraging image-text similarity from vision language model.Scientific reports · 2025Article
- Kinematic correlates of early speech motor changes in cognitively intact APOE-ε4 carriers: a preliminary study using a color-word interference task.Frontiers in neurology · 2025Article
- Adversarial Text Generation using Large Language Models for Dementia Detection.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2024Article
- Analyzing Multimodal Features of Spontaneous Voice Assistant Commands for Mild Cognitive Impairment Detection.Interspeech · 2024Article
- Natural Language Processing Applied to Spontaneous Recall of Famous Faces Reveals Memory Dysfunction in Temporal Lobe Epilepsy Patients.bioRxiv : the preprint server for biology · 2024Article
- The Optimization of a Natural Language Processing Approach for the Automatic Detection of Alzheimer's Disease Using GPT Embeddings.Brain sciences · 2024Article
- The Optimization of a Natural Language Processing Approach for the Automatic Detection of Alzheimer's Disease Using GPT Embeddings.medRxiv : the preprint server for health sciences · 2024Article
- Harnessing Speech-Derived Digital Biomarkers to Detect and Quantify Cognitive Decline Severity in Older Adults.Gerontology · 2024Article
- fMRI-based Alzheimer's disease detection via functional connectivity analysis: a systematic review.PeerJ. Computer science · 2024Article
- The Case of the Cookie Jar: Differences in Typical Language Use in Dementia.Journal of Alzheimer's disease : JAD · 2024Article
- Text Dialogue Analysis for Primary Screening of Mild Cognitive Impairment: Development and Validation Study.Journal of medical Internet research · 2023Article
- ETMT: A Tool for Eye-Tracking-Based Trail-Making Test to Detect Cognitive Impairment.Sensors (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundAlzheimer's disease (AD) has paramount importance due to its rising prevalence, the impact on the patient and society, and the related healthcare costs. However, current diagnostic techniques are not designed for frequent mass screening, delaying therapeutic intervention and worsening prognoses. To be able to detect AD at an early stage, ideally at a pre-clinical stage, speech analysis emerges as a simple low-cost non-invasive procedure.
objectivesIn this work it is our objective to do a systematic review about speech-based detection and classification of Alzheimer's Disease with the purpose of identifying the most effective algorithms and best practices.
methodsA systematic literature search was performed from Jan 2015 up to May 2020 using ScienceDirect, PubMed and DBLP. Articles were screened by title, abstract and full text as needed. A manual complementary search among the references of the included papers was also performed. Inclusion criteria and search strategies were defined a priori.
resultsWe were able: to identify the main resources that can support the development of decision support systems for AD, to list speech features that are correlated with the linguistic and acoustic footprint of the disease, to recognize the data models that can provide robust results and to observe the performance indicators that were reported. DISCUSSION: A computational system with the adequate elements combination, based on the identified best-practices, can point to a whole new diagnostic approach, leading to better insights about AD symptoms and its disease patterns, creating conditions to promote a longer life span as well as an improvement in patient quality of life. The clinically relevant results that were identified can be used to establish a reference system and help to define research guidelines for future developments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.