Evidence map›Paper›PMID 35049730›Full record

ArticleBioengineering (Basel, Switzerland)2022

Impact of Electrospun Piezoelectric Core-Shell PVDFhfp/PDMS Mesh on Tenogenic and Inflammatory Gene Expression in Human Adipose-Derived Stem Cells: Comparison of Static Cultivation with Uniaxial Cyclic Tensile Stretching.

Walter Baumgartner, Petra Wolint, Silvan Hofmann, Cléa Nüesch, Maurizio Calcagni, Marzia Brunelli, Johanna Buschmann

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Unlocking the Potential of Stem Cell Microenvironments In Vitro.Bioengineering (Basel, Switzerland) · 2024
    Review
  6. Advances in mesenchymal stem cells therapy for tendinopathies.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2024
    Review
  7. Review
  8. Article
  9. Advanced Robotics to Address the Translational Gap in Tendon Engineering.Cyborg and bionic systems (Washington, D.C.) · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Walter BaumgartnerDivision of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zurich, Switzerland.
Petra WolintDivision of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zurich, Switzerland.ORCID 0000-0002-9978-1438
Silvan HofmannDivision of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zurich, Switzerland.
Cléa NüeschDivision of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zurich, Switzerland.
Maurizio CalcagniDivision of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zurich, Switzerland.ORCID 0000-0003-4372-0561
Marzia Brunelli2EMPA, CH-9014 St. Gallen, Switzerland.
Johanna BuschmannDivision of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zurich, Switzerland.ORCID 0000-0001-7919-7448
University Hospital of Zurich · CHUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific microenvironments can trigger stem cell tenogenic differentiation, such as specific substrates or dynamic cell cultivation. Electrospun meshes composed by core-shell fibers (random or aligned; PDMS core; piezoelectric PVDFhfp shell) were fabricated by coaxial electrospinning. Elastic modulus and residual strain were assessed. Human ASCs were seeded on such scaffolds either under static conditions for 1 week or with subsequent 10% dynamic stretching for 10,800 cycles (1 Hz, 3 h), assessing load elongation curves in a Bose

Indexed as

adipose-derived stem cellsbioreactorcoaxial electrospinningelastic moduluspolydimethylsiloxanepoly(vinylidene fluoride-co-hexafluoropropylene)residual strain

Identifiers

PMID35049730
PMCPMC8772741
OpenAlexW4206305903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.