Evidence map›Paper›PMID 35049691›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Intraventricular Meningiomas: Clinical-Pathological and Genetic Features of a Monocentric Series.

Serena Ammendola, Michele Simbolo, Chiara Ciaparrone, Paola Chiara Rizzo, Maria Caffo, Giampietro Pinna, Francesco Sala, Aldo Scarpa, Valeria Barresi

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Serena AmmendolaDipartimento di Diagnostica e Sanità Pubblica, Università degli studi di Verona, 371234 Verona, Italy.
Michele SimboloDipartimento di Diagnostica e Sanità Pubblica, Università degli studi di Verona, 371234 Verona, Italy.ORCID 0000-0002-0866-4499
Chiara CiaparroneDipartimento di Diagnostica e Sanità Pubblica, Università degli studi di Verona, 371234 Verona, Italy.
Paola Chiara RizzoDipartimento di Diagnostica e Sanità Pubblica, Università degli studi di Verona, 371234 Verona, Italy.
Maria CaffoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Neurosurgery, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-3240-0506
Giampietro PinnaUnit of Neurosurgery, Department of Neurosciences, Hospital Trust of Verona, 37126 Verona, Italy.
Francesco SalaDepartment of Neurosciences, Biomedicines and Movement Sciences, Institute of Neurosurgery, University of Verona, 37126 Verona, Italy.
Aldo ScarpaDipartimento di Diagnostica e Sanità Pubblica, Università degli studi di Verona, 371234 Verona, Italy.ORCID 0000-0003-1678-739X
Valeria BarresiDipartimento di Diagnostica e Sanità Pubblica, Università degli studi di Verona, 371234 Verona, Italy.ORCID 0000-0001-7086-1920
University of Verona · ITUniversity of Messina · IT

Funding

University of Messina Research and Mobility 2018, to MC and VBUniversity of Verona FUR 2020 to VB
6 · The paper itself

Abstract

Intraventricular meningiomas (IVMs) are rare (0.5-5%) and usually low-grade (90% grade I) brain neoplasms. Their recurrence rate is lower than that of extra-axial meningiomas, but their surgical resection can be burdened with life-threatening complications, which represent the major cause of the reported 4% mortality. The aim of this study is to characterize the molecular portrait of IVMs to identify potential therapeutic targets. For this, we explored mutations and copy number variations (CNV) of 409 cancer-related genes and tumor mutational burden (TMB) of six cases, using next-generation sequencing. Five IVMs were grade I and one was grade II; none recurred, in spite of partial surgical resection in one case.

Indexed as

Meningeal NeoplasmsMeningiomaRadiosurgeryDNA Copy Number VariationsHumansMutationintraventricularmeningiomaNF2SMARCB1TMBtumor mutational burden

Identifiers

PMID35049691
PMCPMC8775267
OpenAlexW4206143026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.