Evidence map›Paper›PMID 35049679›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

HMGA1 Has Predictive Value in Response to Chemotherapy in Gastric Cancer.

Diana Pádua, Débora Filipa Pinto, Paula Figueira, Carlos Filipe Pereira, Raquel Almeida, Patrícia Mesquita

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. The RNA-binding protein YTHDF3 affects gastric cancer cell migration and response to paclitaxel by regulating EZRIN.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Diana Páduai3S-Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-5780-9842
Débora Filipa Pintoi3S-Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.
Paula Figueirai3S-Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.
Carlos Filipe PereiraCNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.
Raquel Almeidai3S-Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.
Patrícia Mesquitai3S-Institute for Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-4766-9831
Universidade do Porto · PTLund University · SE

Funding

Fundação para a Ciência e Tecnologia Norte-01-0145-FEDER-000051Fundação para a Ciência e Tecnologia POCI-01-0145-FEDER-007274Fundação para a Ciência e Tecnologia POCI-01-0145-FEDER-029017Fundação para a Ciência e Tecnologia SFRH/BD/146186/2019
6 · The paper itself

Abstract

Gastric cancer is a serious health problem worldwide. Although its incidence is decreasing, the five-year survival rate remains low. Thus, it is essential to identify new biomarkers that could promote better diagnosis and treatment of patients with gastric cancer. High-mobility group AT-hook 1 (HMGA1) is a non-histone, chromatin-binding protein that has been found overexpressed in several tumor types. It has been correlated with invasion, metastasis, and drug resistance, leading to worse patient survival. The aim of this work was to evaluate the clinical value of HMGA1 in gastric cancer. HMGA1 expression was analyzed by immunohistochemistry in a single hospital series (

Indexed as

HMGA1a ProteinStomach NeoplasmsCell Line, TumorGene Expression Regulation, NeoplasticHumansPrognosisHMGA1a Proteinchemotherapygastric cancerHMGA1predictive valueprognosis

Identifiers

PMID35049679
PMCPMC8774981
OpenAlexW4200435989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.