Evidence map›Paper›PMID 35049659›Full record

ArticleBiosensors2022

Sensing of C-Reactive Protein Using an Extended-Gate Field-Effect Transistor with a Tungsten Disulfide-Doped Peptide-Imprinted Conductive Polymer Coating.

Kai-Hsi Liu, Hung-Yin Lin, James L Thomas, Chen-Yuan Chen, Yen-Ting Chen, Chuen-Yau Chen, Chien-Hsin Yang, Mei-Hwa Lee

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Kai-Hsi LiuDepartment of Electrical Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Hung-Yin LinDepartment of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
James L ThomasDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM 87131, USA.
Chen-Yuan ChenDepartment of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Yen-Ting ChenInterdisciplinary Program of Electrical Engineering and Computer Science, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
Chuen-Yau ChenDepartment of Electrical Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Chien-Hsin YangDepartment of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Mei-Hwa LeeDepartment of Materials Science and Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
National University of Kaohsiung · TWI-Shou University · TWKaohsiung Armed Forces General Hospital · TWNational Taiwan University of Science and Technology · TWUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-reactive protein (CRP) is a non-specific biomarker of inflammation and may be associated with cardiovascular disease. In recent studies, systemic inflammatory responses have also been observed in cases of coronavirus disease 2019 (COVID-19). Molecularly imprinted polymers (MIPs) have been developed to replace natural antibodies with polymeric materials that have low cost and high stability and could thus be suitable for use in a home-care system. In this work, a MIP-based electrochemical sensing system for measuring CRP was developed. Such a system can be integrated with microfluidics and electronics for lab-on-a-chip technology. MIP composition was optimized using various imprinting template (CRP peptide) concentrations. Tungsten disulfide (WS

Indexed as

Molecularly Imprinted PolymersSulfidesTungsten CompoundsC-Reactive ProteinElectrochemical TechniquesElectrodesHumansPeptidesC-Reactive ProteinMolecularly Imprinted PolymersPeptidesSulfidesTungsten Compoundstungsten sulfideC-reactive proteinelectrochemical sensingepitope imprintinghuman serumtungsten disulfide

Identifiers

PMID35049659
PMCPMC8774123
OpenAlexW4206149044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.