Evidence map›Paper›PMID 35049647›Full record

ArticleBiosensors2021

SERS Platform Based on Hollow-Core Microstructured Optical Fiber: Technology of UV-Mediated Gold Nanoparticle Growth.

Anastasiia A Merdalimova, Polina G Rudakovskaya, Timur I Ermatov, Alexander S Smirnov, Sergey S Kosolobov, Julia S Skibina, Polina A Demina, Boris N Khlebtsov, Alexey M Yashchenok, Dmitry A Gorin

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In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anastasiia A MerdalimovaCenter for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 3 Nobel str, 121205 Moscow, Russia.ORCID 0000-0002-6397-8431
Polina G RudakovskayaCenter for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 3 Nobel str, 121205 Moscow, Russia.
Timur I ErmatovCenter for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 3 Nobel str, 121205 Moscow, Russia.
Alexander S SmirnovCenter for Design, Manufacturing and Materials, Skolkovo Institute of Science and Technology, 1 Nobel str, 121205 Moscow, Russia.ORCID 0000-0002-1573-1100
Sergey S KosolobovCenter for Design, Manufacturing and Materials, Skolkovo Institute of Science and Technology, 1 Nobel str, 121205 Moscow, Russia.
Julia S SkibinaSPE LLC Nanostructured Glass Technology, 101 50 Let Oktjabrja str, 410033 Saratov, Russia.
Polina A DeminaFSRC "Crystallography and Photonics" RAS, 59 Leninsky pr., 119333 Moscow, Russia.ORCID 0000-0001-6349-2979
Boris N KhlebtsovSaratov Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), Institute of Biochemistry and Physiology of Plants and Microorganisms, 410049 Saratov, Russia.ORCID 0000-0003-3996-5750
Alexey M YashchenokCenter for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 3 Nobel str, 121205 Moscow, Russia.ORCID 0000-0002-8302-5646
Dmitry A GorinCenter for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 3 Nobel str, 121205 Moscow, Russia.

Funding

Russian Science Foundation 18-79-10198-П
6 · The paper itself

Abstract

Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for biosensing. However, SERS analysis has several concerns: the signal is limited by a number of molecules and the area of the plasmonic substrate in the laser hotspot, and quantitative analysis in a low-volume droplet is confusing due to the change of concentration during quick drying. The usage of hollow-core microstructured optical fibers (HC-MOFs) is thought to be an effective way to improve SERS sensitivity and limit of detection through the effective irradiation of a small sample volume filling the fiber capillaries. In this paper, we used layer-by-layer assembly as a simple method for the functionalization of fiber capillaries by gold nanoparticles (seeds) with a mean diameter of 8 nm followed by UV-induced chloroauric acid reduction. We also demonstrated a simple and quick technique used for the analysis of the SERS platform formation at every stage through the detection of spectral shifts in the optical transmission of HC-MOFs. The enhancement of the Raman signal of a model analyte Rhodamine 6G was obtained using such type of SERS platform. Thus, a combination of nanostructured gold coating as a SERS-active surface and a hollow-core fiber as a microfluidic channel and a waveguide is perspective for point-of-care medical diagnosis based on liquid biopsy and exhaled air analysis.

Indexed as

GoldMetal NanoparticlesMicrofluidicsOptical FibersSpectrum Analysis, RamanGoldbiosensingglass surface modificationgold depositiongold nanoparticleshollow-core microstructured optical fiberlow-volume sensingSERSultraviolet reduction

Identifiers

PMID35049647
PMCPMC8774134

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