Evidence map›Paper›PMID 35049594›Full record

ArticleGels (Basel, Switzerland)2022

Curcuminoid Co-Loading Platinum Heparin-Poloxamer P403 Nanogel Increasing Effectiveness in Antitumor Activity.

Ngoc The Nguyen, Quynh Anh Bui, Hoang Huong Nhu Nguyen, Tien Thanh Nguyen, Khanh Linh Ly, Ha Le Bao Tran, Vu Nguyen Doan, Tran Thi Yen Nhi, Ngoc Hoa Nguyen, Ngoc Hao Nguyen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Curcumin Administration Routes in Breast Cancer Treatment.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Ngoc The NguyenFaculty of Medicine-Pharmacy, Tra Vinh University, Tra Vinh City 87000, Vietnam.
Quynh Anh BuiInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 71500, Vietnam.ORCID 0000-0002-4693-1383
Hoang Huong Nhu NguyenFaculty of Biology and Biotechnology, University of Science-Vietnam National University, Ho Chi Minh City 72700, Vietnam.
Tien Thanh NguyenFaculty of Medicine-Pharmacy, Tra Vinh University, Tra Vinh City 87000, Vietnam.
Khanh Linh LyFaculty of Medicine-Pharmacy, Tra Vinh University, Tra Vinh City 87000, Vietnam.
Ha Le Bao TranFaculty of Biology and Biotechnology, University of Science-Vietnam National University, Ho Chi Minh City 72700, Vietnam.ORCID 0000-0001-5848-1124
Vu Nguyen DoanFaculty of Biology and Biotechnology, University of Science-Vietnam National University, Ho Chi Minh City 72700, Vietnam.
Tran Thi Yen NhiGraduate University of Science and Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City 71500, Vietnam.ORCID 0000-0001-7522-1471
Ngoc Hoa NguyenGerman Vietnamese Technology Center, HCMC University of Food Industry, Ho Chi Minh City 72000, Vietnam.
Ngoc Hao NguyenInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 71500, Vietnam.ORCID 0000-0002-8156-7986
Ngoc Quyen TranInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 71500, Vietnam.
Dinh Trung NguyenInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 71500, Vietnam.ORCID 0000-0002-6775-9500
Tra Vinh University · VNVietnam Academy of Science and Technology · VNVietnam National University Ho Chi Minh City · VNHo Chi Minh City University of Industry and Trade · VNTrường ĐH Nguyễn Tất Thành · VN

Funding

Tra Vinh University 175/HĐ-HĐKH&ĐT.ĐHTV (12/7/2018)
6 · The paper itself

Abstract

Nanosized multi-drug delivery systems provide synergistic effects between drugs and bioactive compounds, resulting in increased overall efficiency and restricted side effects compared to conventional single-drug chemotherapy. In this study, we develop an amphiphilic heparin-poloxamer P403 (HP403) nanogel that could effectively co-load curcuminoid (Cur) and cisplatin hydrate (CisOH) (HP403@CisOH@Cur) via two loading mechanisms. The HP403 nanogels and HP403@CisOH@Cur nanogels were closely analyzed with

Indexed as

heparinMCF-7multi-drug deliverynanogelpoloxamer P403

Identifiers

PMID35049594
PMCPMC8774475
OpenAlexW4206023464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.