ArticleGels (Basel, Switzerland)2022
Soft-Tissue-Mimicking Using Hydrogels for the Development of Phantoms.
Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Characterization of Bubble Cloud Formation and Tissue Ablation Using a High-Frequency Endoscopic Histotripsy System.Ultrasound in medicine & biology · 2026Article
- Dynamic versus Static In Vitro Drug Release Testing of Subcutaneous Implants with Distinct Microstructures.ACS omega · 2026Article
- Edible Scaffolds for Cultivated Meat Production.Advances in biochemical engineering/biotechnology · 2026Review
- Studying Perfusion Effects on Heat Transfer in Tissue-Mimicking Phantoms for Cardiac Ablation: A Preliminary Experimental Investigation.Journal of fluid flow, heat and mass transfer · 2026Article
- Rheology and Moisture-Responsive Adhesion of Hydroxypropyl Cellulose-Enhanced Polyvinylpyrrolidone-Polyethylene Glycol Hydrogels.Gels (Basel, Switzerland) · 2025Article
- A novel thermochromic myocardial phantom for radiofrequency ablation and cryoablation.Scientific reports · 2025Article
- Efficacy of modified technique for 1 cm core needle biopsy using a 2 cm cutting length with coaxial introducer needle.Abdominal radiology (New York) · 2025Article
- Validation and reliability of mechanical stiffness assessment tools in multilayered polyurethane phantom models of healthy and diabetic plantar soft tissues.Scientific reports · 2025Article
- A Cost-Effective 3D-Printed Conductive Phantom for EEG Sensing System Validation: Development, Performance Evaluation, and Comparison with State-of-the-Art Technologies.Sensors (Basel, Switzerland) · 2025Article
- Overcoming Barriers in Neurosurgical Education: Introducing a Simulator for Insular Glioma Resection with Fluorescence Imaging (SIGMA).Journal of clinical medicine · 2025Article
- Molecular Engineering of Direct Activated NIR-II Chemiluminescence Platform for In Vivo Chemiluminescence-fluorescence Duplex Imaging.Nature communications · 2025Article
- The Impact of Helium and Nitrogen Plasmas on Electrospun Gelatin Nanofiber Scaffolds for Skin Tissue Engineering Applications.Journal of functional biomaterials · 2024Article
- Dynamic Light Scattering Microrheology of Phase-Separated Poly(vinyl) Alcohol-Phytagel Blends.Polymers · 2024Article
- Generation of a Human Induced Pluripotent Stem Cell Line Expressing a Magnetic Resonance Imaging Reporter Gene.Small methods · 2024Article
- Fabrication and Characterization of Brain Tissue Phantoms Using Agarose Gels for Ultraviolet Vision Systems.Gels (Basel, Switzerland) · 2024Article
- Morphological Characteristics of Biopolymer Thin Films Swollen-Rich in Solvent Vapors.Biomimetics (Basel, Switzerland) · 2024Article
- Agarose as a Tissue Mimic for the Porcine Heart, Kidney, and Liver: Measurements and a Springpot Model.Bioengineering (Basel, Switzerland) · 2024Article
- Development and characterization of silicone-based tissue phantoms for pulse oximeter performance testing.Journal of biomedical optics · 2024Article
- Bevel-Tip Needle Deflection Modeling, Simulation, and Validation in Multi-Layer Tissues.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2024Article
- Bioactive Polyurethane-Poly(ethylene Glycol) Diacrylate Hydrogels for Applications in Tissue Engineering.Gels (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the currently available materials and technologies it is difficult to mimic the mechanical properties of soft living tissues. Additionally, another significant problem is the lack of information about the mechanical properties of these tissues. Alternatively, the use of phantoms offers a promising solution to simulate biological bodies. For this reason, to advance in the state-of-the-art a wide range of organs (e.g., liver, heart, kidney as well as brain) and hydrogels (e.g., agarose, polyvinyl alcohol -PVA-, Phytagel -PHY- and methacrylate gelatine -GelMA-) were tested regarding their mechanical properties. For that, viscoelastic behavior, hardness, as well as a non-linear elastic mechanical response were measured. It was seen that there was a significant difference among the results for the different mentioned soft tissues. Some of them appear to be more elastic than viscous as well as being softer or harder. With all this information in mind, a correlation between the mechanical properties of the organs and the different materials was performed. The next conclusions were drawn: (1) to mimic the liver, the best material is 1% wt agarose; (2) to mimic the heart, the best material is 2% wt agarose; (3) to mimic the kidney, the best material is 4% wt GelMA; and (4) to mimic the brain, the best materials are 4% wt GelMA and 1% wt agarose. Neither PVA nor PHY was selected to mimic any of the studied tissues.
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