Evidence map›Paper›PMID 35049412›Full record

ArticleHuman vaccines & immunotherapeutics2022

Modeled impact of the COVID-19 pandemic and associated reduction in adult vaccinations on herpes zoster in the United States.

Desmond Curran, Elizabeth M La, Ahmed Salem, David Singer, Nicolas Lecrenier, Sara Poston

Open access · goldAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Desmond CurranGSK, Wavre, Belgium.ORCID 0000-0002-7423-0111
Elizabeth M LaGSK, Philadelphia, PA, USA.ORCID 0000-0001-5652-8961
Ahmed SalemGSK, Wavre, Belgium.ORCID 0000-0003-0704-8085
David SingerGSK, Philadelphia, PA, USA.ORCID 0000-0001-8008-8003
Nicolas LecrenierGSK, Wavre, Belgium.ORCID 0000-0002-0321-6283
Sara PostonGSK, Philadelphia, PA, USA.ORCID 0000-0003-4735-057X
GlaxoSmithKline (Belgium) · BEGlaxoSmithKline (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to COVID-19, vaccinations dropped in 2020 and 2021. We estimated the impact of reduced recombinant zoster vaccine (RZV) use on herpes zoster (HZ) cases, complications, and quality-adjusted life-year (QALY) losses among older adults. Various scenarios were compared with Markov models using data from national sources, clinical trials, and literature. Missed series initiations were calculated based on RZV distributed doses. In 2020, 3.9 million RZV series initiations were missed, resulting in 31,945 HZ cases, 2,714 postherpetic neuralgia cases, and 610 lost QALYs. Scenarios further projected disease burden increases if individuals remain unvaccinated in 2021 or the same number of initiations are missed in 2021. Health professionals should emphasize the importance of vaccination against all preventable diseases during the COVID-19 era.

Indexed as

COVID-19Herpes ZosterHerpes Zoster VaccineNeuralgia, PostherpeticAgedCost-Benefit AnalysisHerpesvirus 3, HumanHumansPandemicsUnited StatesVaccinationVaccines, SyntheticHerpes Zoster VaccineVaccines, SyntheticCOVID-19herpes zosterimmunizationpostherpetic neuralgiapublic healthrecombinant zoster vaccineshinglesvaccine

Identifiers

PMID35049412
PMCPMC8993052
OpenAlexW4206178828

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.