ArticleMedicine2021
Clinico-radiological features of brain metastases from thyroid cancer.
Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- The Anti-Aging Benefits of Phytoestrogens: Insights and Evidence.Current medicinal chemistry · 2026Pooled it
- Diagnostic performance of machine learning and deep learning algorithms for thyroid cancer metastasis: a systematic review and meta-analysis.BMC medical informatics and decision making · 2025Pooled it
- A rare case of isolated metastatic disease in a young woman with papillary thyroid carcinoma and a novel method for diagnosis: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Diagnosis and management of brain metastasis from thyroid cancer.Endocrine oncology (Bristol, England) · 2025Review
- Metastatic follicular thyroid carcinoma to the brain during pregnancy: A neurosurgical and ethical challenge.Surgical neurology international · 2025Article
- Management of anticoagulation in patients with brain metastasis.Hematology. American Society of Hematology. Education Program · 2024Review
- Primary Central Nervous System Lymphoma (PCNSL) Following Thyroid Cancer Surgery: A Case Report of Misdiagnosed Brain Metastasis and Literature Review.Current oncology (Toronto, Ont.) · 2024Review
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- Follicular carcinoma of the thyroid presenting as metastasis in the wall of an arachnoid cyst.BMJ case reports · 2023Article
- Clinical characteristics, treatment, and long-term outcome of patients with brain metastases from thyroid cancer.Clinical & experimental metastasis · 2023Article
- Possible association between minor head injury and intratumoral hemorrhage: A metastatic brain tumor from thyroid carcinoma.Radiology case reports · 2023Article
- Associated Factors of Spontaneous Hemorrhage in Brain Metastases in Patients with Lung Adenocarcinoma.Cancers · 2023Article
- Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series.Thyroid research · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
abstractThe brain is an unusual site for distant metastases of thyroid cancer. The radiological features of brain metastases (BMs) have rarely been reported. Hemorrhage is frequently noted in BMs from thyroid cancer. This study aimed to investigate the clinico-radiological features of BMs from thyroid cancer and to determine the risk factors to predict BM hemorrhage.We retrospectively evaluated the MR images of 35 patients with BMs from thyroid cancer at our hospital from 2013 to 2020. The number, size, site, presence of extra-cranial metastasis, presence of perilesional edema, intra-tumoral hemorrhage, enhancement pattern, and presence of diffusion restriction on MRI were described. We further classified the thyroid cancers into hemorrhagic and nonhemorrhagic groups to investigate the factors associated with hemorrhage.54.29% of patients with thyroid BMs (19/35) had neurologic symptoms. 94.29% of patients (33/35) had extra-cranial metastases. The most common histology of primary thyroid cancer was papillary thyroid cancer (71.43%, 25/35), followed by anaplastic thyroid cancer (22.86%, 8/35). Thyroid cancer BMs were located mostly in the supra-tentorium (51.43%, 18/35) or both the supra and infra-tentorium (45.71%, 16/35). 60% of patients (21/35) showed hemorrhage within the BMs. The strongest predictor for BM hemorrhage was tumor size (variable importance: 50).Thyroid cancer BMs exhibit a bleeding tendency. Furthermore, larger BMs are more likely to have an intra-tumoral hemorrhage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.