ArticleMedicine2021
Risk factors of intracranial infection in patients after intracranial aneurysm surgery: Implication for treatment strategies.
Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 9 citations in OpenAlex.
- Nomogram for Predicting the Risk of Post-Craniotomy Intracranial Infection in Patients With Brain Tumors.Cancer medicine · 2026Article
- CSF Leukocytes in Intracranial Infections: Diagnostic, Mechanistic, and Therapeutic Insights for Neurocritical Care.Cellular and molecular neurobiology · 2026Review
- Individualized treatment for pediatric intracranial aneurysms in China: case series and literature review.Frontiers in surgery · 2026Article
- Predicting Post-Craniotomy Intracranial Infection Using Perioperative and Early Postoperative Variables: A Retrospective Machine Learning Study.International journal of general medicine · 2026Article
- Postoperative brain abscesses and infections after neurosurgery: Clinical characteristics, risk profiles, microbiological findings, and longitudinal DWI and ADC MRI analysis.Brain & spine · 2026Article
- Development and validation of a nomogram for predicting intracranial infection after intracranial aneurysm surgery.Frontiers in neurology · 2025Article
- Predictive value of cerebrospinal fluid heparin-binding protein and CD64 expression for postoperative central nervous system infection following intracerebral hemorrhage surgery.American journal of translational research · 2025Article
- A novel dynamic nomogram based on clinical features and laboratory indicators for diagnosis of post-neurosurgery intracranial infection.Translational neuroscience · 2025Article
- An analysis of the clinical application of paliperidone palmitate injection based on real-world.Frontiers in pharmacology · 2025Article
- Effect of exercise-nutrition-psychology oriented nursing in patients undergoing interventional embolization for intracranial aneurysm.American journal of translational research · 2024Article
- Impact of surgery within 6 hours on preoperative rerupture and prognosis of poor-grade aneurysmal subarachnoid hemorrhage.Frontiers in neurologyArticle
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Authors and funding
3 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractPostoperative intracranial infection after intracranial aneurysm is relatively common in clinical setting; it is necessary to analyze the clinical risk factors of postoperative intracranial infection, to provide reliable evidence to the management of aneurysm.Patients with intracranial aneurysm admitted from January 1, 2016, to November 30, 2020, are included. We collected the patient's personal and treatment data, and analyzed the risk factors of intracranial infection by multivariate logistic regression analysis. We compared the cerebrospinal fluid (CSF) indicators and serological indicators and analyzed their correlation with intracranial infection by spearman analysis.A total of 236 patients with intracranial aneurysm were included; the incidence of postoperative intracranial infection was 12.71%. There were significant differences in the diabetes, intraoperative aneurysm rupture, intraoperative CSF leakage, duration of surgery, and estimated blood loss between infection and non-infection group. Logistic regression indicated that diabetes [odds ratio (OR) 2.053, 95% confidence interval (95% CI) 1.092∼3.385], intraoperative aneurysm rupture (OR 2.239, 95% CI 1.173∼4.312), intraoperative CSF leakage (OR 2.168, 95% CI 1.033∼3.451), duration of surgery ≥360 minutes (OR 1.926, 95% CI 1.108∼2.655), and estimated blood loss ≥125 mL (OR 2.459, 95% CI 1.854∼3.447) were the independent risk factors of postoperative intracranial infection in patients with aneurysm surgery (all P < .05). Klebsiella pneumoniae, Escherichia coli, and Staphylococcus epidermidis were the top 3 commonly seen pathogens. Spearman analyses indicated that PCT, CRP, LA, LDH were all correlated with intracranial infection (all P < .05).There are multiple factors for the postoperative intracranial infection in patients with aneurysm. Coping strategies should be formulated targeted on those risks to improve the prognosis of patients.
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