Evidence map›Paper›PMID 35049149›Full record

ArticleACR open rheumatology2022

Influenza Vaccine Hesitancy and Its Determinants Among Rheumatology Patients.

Valeria Valerio, Marie Hudson, Mianbo Wang, Sasha Bernatsky, Elizabeth M Hazel, Brian Ward, Inés Colmegna

Open access · goldAbstract read
In one paragraph

Article in ACR open rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. The 2022 ACR vaccination guideline: a call-to-action.Nature reviews. Rheumatology · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Valeria ValerioThe Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Marie HudsonLady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada.
Mianbo WangLady Davis Institute, Montreal, Quebec, Canada.
Sasha BernatskyThe Research Institute of the McGill University Health Centre and McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-9515-2802
Elizabeth M HazelMcGill University, Montreal, Quebec, Canada.
Brian WardThe Research Institute of the McGill University Health Centre and McGill University, Montreal, Quebec, Canada.
Inés ColmegnaThe Research Institute of the McGill University Health Centre and McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-8091-8334
McGill University Health Centre · CAJewish General Hospital · CAMcGill University · CA

Funding

McGill University Clinical Research Support - 20191218
6 · The paper itself

Abstract

objectivePatients with rheumatic disease (RD) have an increased risk of influenza and its complications. Despite inactivated influenza vaccine (IIV) recommendations, IIV uptake in patients with RD is suboptimal, a problem of increasing importance in the COVID-19 era. We estimated the frequency of IIV hesitancy and associated factors among Canadian patients with RD.

methodsA cross-sectional vaccine hesitancy survey was completed by rheumatology clinic patients (November 2019 to January 2020). Patients rated their likelihood of receiving the influenza vaccine (scale of 0-10). We categorized these as follows: likely to refuse (scale of 0-2), uncertain (scale of 3-7), or likely to accept (scale of 8-10). Multivariate logistical regression was used to evaluate factors associated with vaccine hesitancy.

resultsA total of 282 patients (63.5% of those approached) completed the survey, with 165 (58.5%) being likely to accept, 67 (23.8%) being likely to refuse, and 50 (17.7%) uncertain. Uncertain patients were younger and more likely to be employed than those in the other two groups. No previous influenza vaccination (odds ratio [OR] 36.6, 95% confidence interval [CI] 5.3-252.9), belief that vaccination should not be mandatory (OR 0.1, 95% CI 0.0-0.7), unwillingness to take time off work to be vaccinated (OR 6.8, 95% CI 1.5-30.6), and distrust in pharmaceutical companies (OR 41.0, 95% CI 5.6-301.5) predicted likeliness to refuse. Reluctance to pay for vaccination (OR 2.8, 95% CI 1.1-7.5) and no previous influenza vaccination (OR 18.9, 95% CI 3.3-109.7) predicted uncertainty.

conclusionMore than 40% of rheumatology patients are either likely to refuse or uncertain about receiving IIV. This contributes to suboptimal vaccine coverage in this population. Interventions addressing these concerns are needed, particularly in the COVID-19 era.

Identifiers

PMID35049149
PMCPMC8992470
OpenAlexW4206620996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.