ArticleMagnetic resonance in medicine2022
Evaluating diffusion dispersion across an extended range of b-values and frequencies: Exploiting gap-filled OGSE shapes, strong gradients, and spiral readouts.
Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
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- Human Brain High-Resolution Diffusion MRI With Optimized, Slice-By-Slice, Zeroth and First OrderMagnetic resonance in medicine · 2026Article
- Strong-Gradient Diffusion-Weighted Imaging of Prostate Cancer Using an Inside-Out Nonlinear Gradient Coil.Magnetic resonance in medicine · 2026Article
- Enhanced spectral response in frequency-dependent diffusion measurements using a linear encoding model.Magnetic resonance in medicine · 2025Article
- Non-monotonic time- and frequency-dependent diffusion kurtosis in the human brain revealed by pulsed and oscillating gradient experiments.Magnetic resonance in medicine · 2025Article
- Feasibility of strong diffusion encoding and fast readout using a plug-and-play head gradient insert at 7 T.Magnetic resonance in medicine · 2025Article
- Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025Review
- Frequency-dependence in multidimensional diffusion-relaxation correlation MRI of the brain: Overfitting or meaningful parameter?Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Robust frequency-dependent diffusional kurtosis computation using an efficient direction scheme, axisymmetric modelling, and spatial regularization.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Variability of multidimensional diffusion-relaxation MRI estimates in the human brain.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- Evaluating diffusion dispersion across an extended range of b-values and frequencies: Exploiting gap-filled OGSE shapes, strong gradients, and spiral readouts.Magnetic resonance in medicine · 2022Article
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Abstract
purposeTo address the long echo times and relatively weak diffusion sensitization that typically limit oscillating gradient spin-echo (OGSE) experiments, an OGSE implementation combining spiral readouts, gap-filled oscillating gradient shapes providing stronger diffusion encoding, and a high-performance gradient system is developed here and utilized to investigate the tradeoff between b-value and maximum OGSE frequency in measurements of diffusion dispersion (i.e., the frequency dependence of diffusivity) in the in vivo human brain. In addition, to assess the effects of the marginal flow sensitivity introduced by these OGSE waveforms, flow-compensated variants are devised for experimental comparison.
methodsUsing DTI sequences, OGSE acquisitions were performed on three volunteers at b-values of 300, 500, and 1000 s/mm
resultsThe power law diffusion dispersion model was found to fit best to MD measurements acquired at b = 1000 s/mm
conclusionThe presented OGSE implementation provided an improved depiction of diffusion dispersion and demonstrated the advantages of measuring dispersion at higher b-values rather than higher frequencies within the regimes employed in this study.
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