Evidence map›Paper›PMID 35048862›Full record

ArticleThe British journal of psychiatry : the journal of mental science2021

The healthcare resource impact of maternal mental illness on children and adolescents: UK retrospective cohort study.

Holly Hope, Cemre Su Osam, Evangelos Kontopantelis, Sian Hughes, Luke Munford, Darren M Ashcroft, Matthias Pierce, Kathryn M Abel

Open access · hybridAbstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Holly HopeCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, UK.ORCID 0000-0002-4834-6719
Cemre Su OsamCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, UK.
Evangelos KontopantelisDivision of Informatics, Faculty of Biology, Medicine and Health, University of Manchester, UK.ORCID 0000-0001-6450-5815
Sian HughesCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, UK; and Population Health Analysis, Department of Health and Social Care, UK.
Luke MunfordDivision of Population Health, Health Services Research & Primary Care, Faculty of Biology, Medicine and Health, University of Manchester, UK.
Darren M AshcroftCentre for Pharmacoepidemiology and Drug Safety, Faculty of Biology, Medicine and Health, University of Manchester, UK.
Matthias PierceCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, UK.ORCID 0000-0003-2182-0369
Kathryn M AbelCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, UK; and Greater Manchester Mental Health NHS Foundation Trust, UK.
University of Manchester · GBDepartment of Health and Social Care · GBGreater Manchester Mental Health NHS Foundation Trust · GBManchester Academic Health Science Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe general health of children of parents with mental illness is overlooked.

aimsTo quantify the difference in healthcare use of children exposed and unexposed to maternal mental illness (MMI).

methodThis was a retrospective cohort study of children aged 0-17 years, from 1 April 2007 to 31 July 2017, using a primary care register (Clinical Practice Research Datalink) linked to Hospital Episodes Statistics. MMI included non-affective/affective psychosis and mood, anxiety, addiction, eating and personality disorders. Healthcare use included prescriptions, primary care and secondary care contacts; inflation adjusted costs were applied. The rate and cost was calculated and compared for children exposed and unexposed to MMI using negative binomial regression models. The total annual cost to NHS England of children with MMI was estimated.

resultsThe study included 489 255 children: 238 106 (48.7%) girls, 112 741 children (23.0%) exposed to MMI. Compared to unexposed children, exposed children had a higher rate of healthcare use (rate ratio 1.27, 95% CI 1.26-1.28), averaging 2.21 extra contacts per exposed child per year (95% CI 2.14-2.29). Increased healthcare use among exposed children occurred in inpatients (rate ratio 1.37, 95% CI 1.32-1.42), emergency care visits (rate ratio 1.34, 95% CI 1.33-1.36), outpatients (rate ratio 1.30, 95% CI 1.28-1.32), prescriptions (rate ratio 1.28, 95% CI 1.26-1.30) and primary care consultations (rate ratio 1.24, 95% CI 1.23-1.25). This costs NHS England an additional £656 million (95% CI £619-£692 million), annually.

conclusionsChildren of mentally ill mothers are a health vulnerable group for whom targeted intervention may create benefit for individuals, families, as well as limited NHS resources.

Indexed as

Mental DisordersAdolescentAnxiety DisordersChildDelivery of Health CareEnglandFemaleHumansRetrospective StudiesDepressive disordersin-patient treatmentout-patient treatmentprimary carepsychotic disorders

Identifiers

PMID35048862
PMCPMC8387858
OpenAlexW3165658911

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.