Evidence map›Paper›PMID 35048323›Full record

ArticleJournal of physiology and biochemistry2022

D609 inhibition of phosphatidylcholine-specific phospholipase C attenuates prolonged insulin stimulation-mediated GLUT4 downregulation in 3T3-L1 adipocytes.

Jinhui Ma, Xu Zhang, Yankun Song, Yan Qin, Yinghui Tan, Lishuang Zheng, Baoqian Cheng, Xin Xi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physiology and biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jinhui MaDepartment of Endocrinology, Affiliated Hospital of Hebei University, Baoding, 071000, China.
Xu ZhangBaoding Maternal and Child Hospital, Baoding, 071000, China.
Yankun SongSchool of Medicine, Hebei University, Baoding, 071000, China.
Yan QinCentral Laboratory, Affiliated Hospital of Hebei University, Baoding, 071000, China.
Yinghui TanCentral Laboratory, Affiliated Hospital of Hebei University, Baoding, 071000, China.
Lishuang ZhengCentral Laboratory, Affiliated Hospital of Hebei University, Baoding, 071000, China.
Baoqian ChengSchool of Medicine, Hebei Medical University, Shijiazhuang, 050017, China.
Xin XiCentral Laboratory, Affiliated Hospital of Hebei University, Baoding, 071000, China. xixin@hbu.edu.cn.ORCID http://orcid.org/0000-0002-7917-485X
Affiliated Hospital of Hebei University · CNBaoding People's Hospital · CNHebei Medical University · CNHebei University · CN

Funding

Key Project Plan of Medical Science Research in Hebei Province, China 20180706Key Research and Development Project of Hebei Province, China 182777105DNational Natural Science Foundation of China 31701238
6 · The paper itself

Abstract

Glucose uptake is stimulated by insulin via stimulation of glucose transporter 4 (GLUT4) translocation to the plasma membrane from intracellular compartments in adipose tissue and muscles. Insulin stimulation for prolonged periods depletes GLUT4 protein, particularly in highly insulin-responsive GLUT4 storage vesicles. This depletion mainly occurs via H

Indexed as

Glucose Transporter Type 4InsulinNorbornanesThiocarbamatesType C Phospholipases3T3-L1 CellsAdipocytesAnimalsDown-RegulationGlucoseHydrogen PeroxideMiceGlucoseGlucose Transporter Type 4Hydrogen PeroxideInsulinNorbornanesphosphatidylcholine-specific phospholipase CSlc2a4 protein, mouseThiocarbamatestricyclodecane-9-yl-xanthogenateType C Phospholipases3T3-L1 adipocytesGlucose transporter 4Insulin stimulationPhosphatidylcholine-specific phospholipase C

Identifiers

PMID35048323
PMCPMC9242966
OpenAlexW4205744496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.