Evidence map›Paper›PMID 35048077›Full record

ArticleFrontiers in oral health2021

Tetramic Acids Mutanocyclin and Reutericyclin A, Produced by

Carla Uranga, Karen E Nelson, Anna Edlund, Jonathon L Baker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Epigenomics identifies three sources of DNA methylation inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. [Latest Findings on Polyketides/Non-ribosomal Peptides That Are Secondary Metabolites ofSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Review
  9. Journal of bacteriology · 2022
    Article
  10. Ecological influence by colonization of fluoride-resistantFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carla UrangaGenomic Medicine Group, J. Craig Venter Institute, La Jolla, CA, United States.
Karen E NelsonGenomic Medicine Group, J. Craig Venter Institute, La Jolla, CA, United States.
Anna EdlundGenomic Medicine Group, J. Craig Venter Institute, La Jolla, CA, United States.
Jonathon L BakerGenomic Medicine Group, J. Craig Venter Institute, La Jolla, CA, United States.
J. Craig Venter Institute · USUniversity of California, San Diego · US

Funding

Investigating Oral Pathogen Virulence within Complex Oral Biofilm CommunitiesR00DE024543 · NIDCR · J. CRAIG VENTER INSTITUTE, INC. · PI EDLUND, ANNA ELISABET · 2016 to 2018
$732k
Exploring the Ecological Roles of Mutanic Acid and Mutanicyclin; Two Novel Small Molecules Produced by Streptococcus mutansR21DE028609 · NIDCR · J. CRAIG VENTER INSTITUTE, INC. · PI NELSON, KAREN E. · 2019 to 2020
$536k
Investigating Membrane Alterations as a Mechanism of Acid Tolerance in Cariogenic BacteriaK99DE029228 · NIDCR · J. CRAIG VENTER INSTITUTE, INC. · PI BAKER, JONATHON · 2020 to 2022
$393k
Understanding S. Mutans Pathogenesis in a Social and Ecological SettingF32DE026947 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BAKER, JONATHON · 2017 to 2020
$186k
NIDCR NIH HHS F32 DE026947NIDCR NIH HHS K99 DE029228NIDCR NIH HHS R00 DE024543NIDCR NIH HHS R21 DE028609
6 · The paper itself

Abstract

The human oral microbiome consists of diverse microbes actively communicating and interacting through a variety of biochemical mechanisms. Dental caries is a major public health issue caused by fermentable carbohydrate consumption that leads to dysbiosis of the oral microbiome.

Indexed as

biofilmdental cariesoral microbiomeoral microbiotaStreptococcus mutans (S. mutans)tetramic acid

Identifiers

PMID35048077
PMCPMC8757879
OpenAlexW4205483354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.