Evidence map›Paper›PMID 35047883›Full record

ReviewFrontiers in medical technology2020

Alec T Salminen, Zahra Allahyari, Shayan Gholizadeh, Molly C McCloskey, Raquel Ajalik, Renee N Cottle, Thomas R Gaborski, James L McGrath

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medical technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. [Force-regulation mechanism of E-selectin mediated adhesion and activation of MDA-MB-231 cells under fluid shear stress].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Pro-Tumorigenic and Thrombotic Activities of Platelets in Lung Cancer.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Integration of immune cells in organs-on-chips: a tutorial.Frontiers in bioengineering and biotechnology · 2023
    Review
  16. Review
  17. Article
  18. Sourcing cells forFrontiers in medical technology · 2022
    Review
  19. Where the Action Is-Leukocyte Recruitment in Atherosclerosis.Frontiers in cardiovascular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alec T SalminenBiomedical Engineering, University of Rochester, Rochester, NY, United States.
Zahra AllahyariBiomedical Engineering, Rochester Institute of Technology, Rochester, NY, United States.
Shayan GholizadehBiomedical Engineering, Rochester Institute of Technology, Rochester, NY, United States.
Molly C McCloskeyBiomedical Engineering, University of Rochester, Rochester, NY, United States.
Raquel AjalikBiomedical Engineering, University of Rochester, Rochester, NY, United States.
Renee N CottleBioengineering, Clemson University, Clemson, SC, United States.
Thomas R GaborskiBiomedical Engineering, University of Rochester, Rochester, NY, United States.
James L McGrathBiomedical Engineering, University of Rochester, Rochester, NY, United States.
University of Rochester · USRochester Institute of Technology · USClemson University · US

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCHT32HL066988 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N, O'REILLY, MICHAEL A · 2001 to 2021
$8.1M
Transparent Ultrathin Nanomembranes for Barrier Cell Models and Novel Co-Culture SystemsR35GM119623 · NIGMS · ROCHESTER INSTITUTE OF TECHNOLOGY · PI GABORSKI, THOMAS R · 2016 to 2020
$2.0M
A microphysiological system of tendon inflammation and fibrosis for drug screening and efficacy testing: MPS Database EngagementUG3TR003281 · NCATS · UNIVERSITY OF ROCHESTER · PI AWAD, HANI A, MCGRATH, JAMES L · 2020 to 2021
$1.6M
Commercializing the µSIM: A Modular Platform for the Development and Analysis of Barrier Tissue ModelsR43GM137651 · NIGMS · SIMPORE, INC. · PI ROUSSIE, JAMES ANDREW · 2020 to 2020
$235k
NCATS NIH HHS UG3 TR003281NHLBI NIH HHS T32 HL066988NIGMS NIH HHS P20 GM103499NIGMS NIH HHS R35 GM119623NIGMS NIH HHS R43 GM137651
6 · The paper itself

Abstract

Inflammatory diseases and cancer metastases lack concrete pharmaceuticals for their effective treatment despite great strides in advancing our understanding of disease progression. One feature of these disease pathogeneses that remains to be fully explored, both biologically and pharmaceutically, is the passage of cancer and immune cells from the blood to the underlying tissue in the process of extravasation. Regardless of migratory cell type, all steps in extravasation involve molecular interactions that serve as a rich landscape of targets for pharmaceutical inhibition or promotion. Transendothelial migration (TEM), or the migration of the cell through the vascular endothelium, is a particularly promising area of interest as it constitutes the final and most involved step in the extravasation cascade. While

Indexed as

drug discoveryextravasationhepatocyte transplantationin vitro platformsleukocytesmetastasisporous membranestransendothelial migration

Identifiers

PMID35047883
PMCPMC8757899
OpenAlexW3100182587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.