Evidence map›Paper›PMID 35047841›Full record

ArticleHGG advances2021

Genetic ancestry and ethnic identity in Ecuador.

Shashwat Deepali Nagar, Andrew B Conley, Aroon T Chande, Lavanya Rishishwar, Shivam Sharma, Leonardo Mariño-Ramírez, Gabriela Aguinaga-Romero, Fabricio González-Andrade, I King Jordan

Abstract read
In one paragraph

Article in HGG advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
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  5. Observational
  6. Observational
  7. Pharmacogenetics and Molecular Ancestry ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  8. Altitude and risk of pre-eclampsia: insights from a large-scale epidemiological study in Ecuador.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
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  13. Review
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  15. Article
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  19. Single nucleotide variants in theFrontiers in cellular and infection microbiology · 2024
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shashwat Deepali NagarSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
Andrew B ConleyPanAmerican Bioinformatics Institute, Cali, Valle del Cauca, Colombia.
Aroon T ChandeSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
Lavanya RishishwarPanAmerican Bioinformatics Institute, Cali, Valle del Cauca, Colombia.
Shivam SharmaNational Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Leonardo Mariño-RamírezPanAmerican Bioinformatics Institute, Cali, Valle del Cauca, Colombia.
Gabriela Aguinaga-RomeroFaculty of Medical Sciences, Central University of Ecuador, Quito, Ecuador.
Fabricio González-AndradeFaculty of Medical Sciences, Central University of Ecuador, Quito, Ecuador.
I King JordanSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the ancestral origins of four Ecuadorian ethnic groups-Afro-Ecuadorian, Mestizo, Montubio, and the Indigenous Tsáchila-in an effort to gain insight on the relationship between ancestry, culture, and the formation of ethnic identities in Latin America. The observed patterns of genetic ancestry are largely concordant with ethnic identities and historical records of conquest and colonization in Ecuador. Nevertheless, a number of exceptional findings highlight the complex relationship between genetic ancestry and ethnicity in Ecuador. Afro-Ecuadorians show far less African ancestry, and the highest levels of Native American ancestry, seen for any Afro-descendant population in the Americas. Mestizos in Ecuador show high levels of Native American ancestry, with substantially less European ancestry, despite the relatively low Indigenous population in the country. The recently recognized Montubio ethnic group is highly admixed, with substantial contributions from all three continental ancestries. The Tsáchila show two distinct ancestry subgroups, with most individuals showing almost exclusively Native American ancestry and a smaller group showing a Mestizo characteristic pattern. Considered together with historical data and sociological studies, our results indicate the extent to which ancestry and culture interact, often in unexpected ways, to shape ethnic identity in Ecuador.

Indexed as

Afro-EcuadorianEcuadorethnicitygenetic ancestrygenomicsIndigenousLatin AmericaMestizoMontubiopopulation genetics

Identifiers

PMID35047841
PMCPMC8756502

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.