ArticleHGG advances2020
Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis.
Open access · goldAbstract read
In one paragraph
Article in HGG advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Iron, inflammation, and intestinal tumors: the crucial triad in colorectal cancer progression and therapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Article
- The Role of Reactive Oxygen Species in Colorectal Cancer Initiation and Progression: Perspectives on Theranostic Approaches.Cancers · 2025Review
- Chronic hepatitis B complicated with secondary hemochromatosis was cured clinically: A case report.Open medicine (Warsaw, Poland) · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
61 authors at 20 institutions in 13 countries.
Gail P JarvikUniversity of Washington Medical Center, Seattle, WA, USA.
Xiaoliang WangFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Pierre Fontanillas23andMe, Sunnyvale, CA, USA.
Esther Kim23andMe, Sunnyvale, CA, USA.
Sirisak ChanprasertUniversity of Washington Medical Center, Seattle, WA, USA.
Adam S GordonNorthwestern University, Evanston, IL, USA.
Lisa BastaracheVanderbilt Medical Center, Atlanta, GA, USA.
Kris V KowdleyLiver Institute Northwest, Seattle, WA, USA.
Tabitha HarrisonFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Elisabeth A RosenthalUniversity of Washington Medical Center, Seattle, WA, USA.
Ian B StanawayUniversity of Washington Medical Center, Seattle, WA, USA.
Stéphane BézieauCentre Hospitalier Universitaire (CHU) Nantes, France.
Stephanie J WeinsteinNational Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Polly A NewcombFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Graham CaseyUniversity of Virginia, Charlottesville, VA, USA.
Elizabeth A PlatzJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kala VisvanathanJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Loic Le MarchandUniversity of Hawaii Cancer Center, Honolulu, HI, USA.
Cornelia M UlrichUniversity of Utah, Salt Lake City, UT, USA.
Sheetal HardikarUniversity of Utah, Salt Lake City, UT, USA.
Christopher I LiFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Franzel J B van DuijnhovenDivision of Human Nutrition and Health, Wageningen University and Research Wageningen, the Netherlands.
Andrea GsurMedical University Vienna, Vienna, Austria.
Peter T CampbellAmerican Cancer Society, Atlanta, GA, USA.
Victor MorenoOncology Data Analytics Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP) and Department of Clinical Sciences, Faculty of Medicine, University of Barcelona (UB), L'Hospitalet, 08908, Barcelona, Spain.
Pavel VodičkaInstitute of Experimental Medicine, Czech Academy of Sciences, Biomedical Center, Medical Faculty Pilsen and 1st Medical Faculty, Charles University, Prague, Czech Republic.
Hermann BrennerGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Jenny Chang-ClaudeGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Michael HoffmeisterGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Martha L SlatteryUniversity of Utah, Salt Lake City, UT, USA.
Marc J GunterNutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France.
Elom K AglagoNutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France.
Sergi Castellví-BelGastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
Sun-Seog KweonChonnam National University Medical School, Gwangju, Korea.
Andrew T ChanClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Li LiUniversity of Virginia, Charlottesville, VA, USA.
Wei ZhengDivision of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
D Timothy BishopUniversity of Leeds, Leeds, UK.
Graham G GilesCancer Council Victoria, Melbourne, VIC, Australia.
Gad RennertLady Davis Carmel Medical Center, Haifa, Israel.
Kenneth OffitMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Temitope O KekuUniversity of North Carolina, Chapel Hill, NC, USA.
Michael O WoodsMemorial University of Newfoundland, St. John's, NL, Canada.
Jochen HampeTechnische Universität Dresden (TU Dresden), Dresden, Germany.
Bethan Van GuelpenDepartment of Radiation Sciences, Oncology, Umeå University and Wallenberg Centre for Molecular Medicine, Umeå University, Sweden.
Steven J GallingerUniversity of Toronto, Toronto, ON, Canada.
Albert de la ChapelleThe Ohio State University, Columbus, OH, USA.
Heather HampelThe Ohio State University, Columbus, OH, USA.
Sonja I BerndtNational Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Catherine M TangenFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Annika LindblomKarolinska University Hospital, Stockholm, Sweden.
Alicja WolkKarolinska Institutet, Stockholm, Sweden.
Andrea Burnett-HartmanKaiser Permanente Colorado, Denver, CO, USA.
Anna H WuUniversity of Southern California, Los Angeles, CA, USA.
Emily WhiteFred Hutchinson Cancer Research Center, Seattle, WA, USA.
23andMe Research Team
Stephen B GruberCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Mark A JenkinsCentre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, VIC, Australia.
Joanna Mountain23andMe, Sunnyvale, CA, USA.
Ulrike PetersFred Hutchinson Cancer Research Center, Seattle, WA, USA.
David R CrosslinUniversity of Washington Medical Center, Seattle, WA, USA.
Fred Hutch Cancer Center · USInstitut d'Investigació Biomédica de Bellvitge · ESUniversity of Washington Medical Center · USUniversity of Utah · US23andMe (United States) · USHeidelberg University · DECentre International de Recherche sur le Cancer · FRJohns Hopkins University · USNational Cancer Institute · USThe Ohio State University · USAmerican Cancer Society · USCarmel Medical Center · ILCentre Hospitalier Universitaire de Nantes · FRChonnam National University · KRConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESCzech Academy of Sciences, Institute of Experimental Medicine · CZKaiser Permanente · USKarolinska University Hospital · SELiver Institute Northwest · USMedical University of Vienna · AT
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4MTranslational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4MMolecular pathological epidemiology of colorectal cancerU01CA137088 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PETERS, ULRIKE · 2009 to 2018
$21.8MVariation, Function, and Disease Supplement ProgramU01HG008657 · NHGRI · UNIVERSITY OF WASHINGTON · PI David Russell Crosslin, Gail Pairitz Jarvik · 2015 to 2026
$13.4MGenome-Wide Association Study of Nonsynonymous SNPs in Colon CancerR01CA059045 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PETERS, ULRIKE · 1994 to 2011
$11.5MPCPT and SELECT Cohorts: Core Infrastructure Support for Cancer ResearchU01CA182883 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TANGEN, CATHERINE M., THOMPSON, IAN M. · 2019 to 2023
$5.4MCancer Research UK 19167NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA059045NCI NIH HHS U01 CA137088NCI NIH HHS U01 CA182883NHGRI NIH HHS U01 HG008657NHLBI NIH HHS HHSN268201200008CNHLBI NIH HHS HHSN268201200008IWorld Health Organization 001
Abstract
Homozygotes for the higher penetrance hemochromatosis risk allele,
Indexed as
age of onsetcolon cancerferritingeneticHFE geneironpopulation screening
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What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.