Evidence map›Paper›PMID 35047739›Full record

ArticleEuropean heart journal. Case reports2021

Mechanical circulatory support and intravascular lithotripsy in high-risk patients undergoing percutaneous coronary intervention and transcatheter aortic valve replacement: a case series.

Alfredo Marchese, Giuseppe Tarantini, Antonio Tito, Vito Margari, Fabrizio Resta, Ilir Dhojniku, Domenico Paparella, Giuseppe Speziale

Open access · goldAbstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Effect of Mechanical Circulatory Support on Mortality After Transcatheter Aortic Valve Replacement: An Analysis.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2025
    Article
  2. Article
  3. Intravascular lithotripsy in coronary arteries: a review of case reports.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Intravascular Lithotripsy for Calcified Left Main Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alfredo MarcheseOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.ORCID https://orcid.org/0000-0002-3445-0865
Giuseppe TarantiniDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua, Via Giustiniani, 2. 35128 Padova, Italy.
Antonio TitoOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.ORCID https://orcid.org/0000-0001-6009-6815
Vito MargariOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.
Fabrizio RestaOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.
Ilir DhojnikuOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.
Domenico PaparellaOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.ORCID https://orcid.org/0000-0003-2261-7098
Giuseppe SpezialeOspedale Santa Maria, GVM Care & Research, Via Antonio De Ferrariis 22, 70124 Bari, Italy.
Ospedale Santa Maria · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients undergoing transcatheter aortic valve replacement (TAVR) usually have multiple comorbidities, such as severely impaired left ventricular function (LVF) and heavily calcified coronary lesions. When they undergo pre-TAVR high-risk percutaneous coronary interventions (HR-PCIs) for severely calcified left main (LM) lesions, potential life-threatening intra-procedural complications associated with the different techniques available to treat calcified lesions can arise. In this setting, mechanical circulatory support proves its usefulness. However, the choice of device can be troublesome. CASE SUMMARY: We report two clinical scenarios of intravascular lithotripsy (IVL) for the treatment of heavily calcified LM coronary lesions, wherein peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO), alone or combined with an intra-aortic balloon pump (IABP), were used as an upfront strategy to support the procedure. The use of these techniques was particularly effective during multi-vessel HR-PCIs and TAVR, and no complications occurred, which suggested their safety. DISCUSSION: These cases provide multiple insights into the strategy of using IVL + VA-ECMO, alone or with IABP, to treat heavily calcified LM coronary lesions in patients with severely compromised LVF undergoing TAVR. IVL safely and effectively overcame shortcomings related to other plaque ablation techniques, and VA-ECMO proved to be effective when facing the combination of high-risk coronary and valve interventions.

Indexed as

3.1 Coronary artery disease4.2 Aortic stenosis6.2 Heart failure with reduced ejection fractionCase seriesExtracorporeal membrane oxygenationIntra-aortic balloon pumpIntravascular lithoplastyMechanical circulatory supportTranscatheter aortic valve replacement

Identifiers

PMID35047739
PMCPMC8759477
OpenAlexW4200182301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.