Evidence map›Paper›PMID 35047711›Full record

ArticleCurrent opinion in physiology2021

Variation in taste ganglion neuron morphology: insights into taste function and plasticity.

Lisa C Ohman, Robin F Krimm

Open access · greenAbstract read
In one paragraph

Article in Current opinion in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lisa C OhmanDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, KY 40202, United States.
Robin F KrimmDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, KY 40202, United States.
University of Louisville · US

Funding

Regulation of taste neuron morphology and functionR01DC007176 · NIDCD · UNIVERSITY OF LOUISVILLE · PI Robin Frances Krimm · 2005 to 2026
$8.1M
Taste neuron connectivity and branching revealed by sparse cell genetic labelingR21DC014857 · NIDCD · UNIVERSITY OF LOUISVILLE · PI KRIMM, ROBIN FRANCES · 2015 to 2016
$400k
Connectivity of periperal taste neuronsF31DC017660 · NIDCD · UNIVERSITY OF LOUISVILLE · PI OHMAN, LISA C · 2018 to 2021
$103k
NIDCD NIH HHS F31 DC017660NIDCD NIH HHS R01 DC007176NIDCD NIH HHS R21 DC014857
6 · The paper itself

Abstract

Chemical information from food is transduced by cells in the taste bud (taste-transducing cells) and carried to the brain by peripheral taste ganglion neurons. These neurons are thought to act simply as cables without any transformation of the signal or circuitry between the taste-transducing cells and the neurons. However, these neurons vary in structure, particularly in the extent of their peripheral axon branching. Such structural differences would be expected to underlie differences in the number of taste-transducing cells providing convergent information to these neurons. However, axon branching may vary over time and morphological differences between neurons might also reflect neuron plasticity. Because taste-transducing cells die and are replaced, the morphology of neurons may change as they form connections with new cells within the taste bud. Modern genetic approaches may permit investigations of the complex relationship among gustatory neuron morphology, circuitry, and function. This review discusses potential relationships among peripheral taste neuron morphology, function, and plasticity to help advance our understanding of taste system function and dysfunction.

Identifiers

PMID35047711
PMCPMC8765802
OpenAlexW3122644691

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.