Evidence map›Paper›PMID 35047665›Full record

ArticleTransplantation direct2022

Solid Organ Transplantation From SARS-CoV-2-infected Donors to Uninfected Recipients: A Single-center Experience.

Channa R Jayasekera, Holenarasipur R Vikram, Zeeshan Rifat, Josiah Wagler, Keita Okubo, Brandon R Braaksma, Jack W Harbell, Caroline C Jadlowiec, Nitin N Katariya, Amit K Mathur and 11 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Utilization of COVID-19 positive donors for Heart transplantation and associated short-term outcomes.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Organ transplantation using COVID-19-positive deceased donors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  9. Utilization and outcomes of deceased donor SARS-CoV-2-positive organs for solid organ transplantation in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Channa R JayasekeraDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Holenarasipur R VikramDivision of Infectious Diseases, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Zeeshan RifatDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Josiah WaglerDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Keita OkuboDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Brandon R BraaksmaDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Jack W HarbellDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Caroline C JadlowiecDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Nitin N KatariyaDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Amit K MathurDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Adyr MossDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
K Sudhakar ReddyDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Andrew SingerDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Robert OrensteinDivision of Infectious Diseases, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Christopher F SalingDivision of Infectious Diseases, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Maria T SevilleDivision of Infectious Diseases, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Girish K MourDivision of Nephrology, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Hugo E VargasDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Thomas J ByrneDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Winston R HewittDivision of Transplant Surgery, Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ.
Bashar A AqelDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Arizona, Phoenix, AZ.
Mayo Clinic in Arizona · USMayo Clinic Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe risk of donor-derived severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in solid organ (heart, lung, liver, kidney, pancreas, and intestine) transplant recipients is poorly understood. Since hematogenous transmission of SARS-CoV-2 has not been documented to date, nonlung solid organs might be suitable for transplantation since they likely portend a low risk of viral transmission.

methodsAbdominal solid organs from SARS-CoV-2-infected donors were transplanted into uninfected recipients.

resultsBetween April 18, 2021, and October 30, 2021, we performed transplants of 2 livers, 1 simultaneous liver and kidney, 1 kidney, and 1 simultaneous kidney and pancreas from SARS-CoV-2-infected donors into 5 uninfected recipients. None of the recipients developed SARS-CoV-2 infection or coronavirus disease 2019, and when tested, allograft biopsies showed no evidence of SARS-CoV-2 RNA.

conclusionsTransplanting nonlung organs from SARS-CoV-2-infected donors into uninfected recipients demonstrated no evidence of virus transmission.

Identifiers

PMID35047665
PMCPMC8759616
OpenAlexW4205917722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.