ArticleWorld journal of clinical cases2021
Association between neutrophil-to-lymphocyte ratio and major postoperative complications after carotid endarterectomy: A retrospective cohort study.
Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 8 citations in OpenAlex.
- Development and validation of a nomogram to pediatric postoperative pulmonary complications following thoracic surgery.BMC anesthesiology · 2025Trial
- The association between sarcopenia and carotid artery plaque: a mediation analysis of inflammatory biomarkers.BMC endocrine disorders · 2026Article
- Association of Radiomics and Pericarotid Adipose Tissue Characteristics with Systemic Inflammation in Patients Undergoing Carotid Endarterectomy.Journal of clinical medicine · 2025Article
- Article
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Authors and funding
6 authors at 1 institution in 1 country.
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Abstract
backgroundCarotid artery cross-clamping during carotid endarterectomy (CEA) may damage local cerebral perfusion and induce cerebral ischemia-reperfusion injury to activate local inflammatory responses. Neutrophil-to-lymphocyte ratio (NLR) is an indicator that reflects systemic inflammation. However, the correlation between NLR and complications after CEA remains unclear.
aimTo investigate the association between NLR and major complications after surgery in patients undergoing CEA.
methodsThis retrospective cohort study included patients who received CEA between January 2016 and July 2018 at Beijing Tiantan Hospital. Neutrophil and lymphocyte counts in whole blood within 24 h after CEA were collected. The primary outcome was the composite of major postoperative complications including neurological, pulmonary, cardiovascular and acute kidney injuries. The secondary outcomes included infections, fever, deep venous thrombosis, length of hospitalization and cost of hospitalization. Statistical analyses were performed using EmpowerStats software and R software.
resultsA total of 224 patients who received CEA were screened for review and 206 were included in the statistical analyses; of whom, 40 (19.42%) developed major postoperative complications. NLR within 24 h after CEA was significantly correlated with major postoperative complications (
conclusionNLR is associated with major postoperative complications in patients undergoing CEA.
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