Evidence map›Paper›PMID 35047496›Full record

ReviewFrontiers in cell and developmental biology2021

The Regulation of Growth in Developing, Homeostatic, and Regenerating Tetrapod Limbs: A Minireview.

Kaylee M Wells, Mary Baumel, Catherine D McCusker

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kaylee M WellsDepartment of Biology, College of Science and Mathematics, University of Massachusetts Boston, Boston, MA, United States.
Mary BaumelDepartment of Biology, College of Science and Mathematics, University of Massachusetts Boston, Boston, MA, United States.
Catherine D McCuskerDepartment of Biology, College of Science and Mathematics, University of Massachusetts Boston, Boston, MA, United States.

Funding

The function of chromatin remodeling in the patterning of the salamander limb regenerateR15HD092180 · NICHD · UNIVERSITY OF MASSACHUSETTS BOSTON · PI MCCUSKER, CATHERINE D · 2018 to 2025
$1.5M
NICHD NIH HHS R15 HD092180
6 · The paper itself

Abstract

The size and shape of the tetrapod limb play central roles in their functionality and the overall physiology of the organism. In this minireview we will discuss observations on mutant animal models and humans, which show that the growth and final size of the limb is most impacted by factors that regulate either limb bud patterning or the elongation of the long bones. We will also apply the lessons that have been learned from embryos to how growth could be regulated in regenerating limb structures and outline the challenges that are unique to regenerating animals.

Indexed as

growth regulationlimb developmentlimb regenerationlong bone growthpatterning

Identifiers

PMID35047496
PMCPMC8763381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.