Evidence map›Paper›PMID 35047453›Full record

ArticleJournal of cancer prevention2021

Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (

Kushal Kandhari, Sandeep Paudel, Komal Raina, Chapla Agarwal, Rama Kant, Michael F Wempe, Cindy O'Bryant, Rajesh Agarwal

Abstract read
In one paragraph

Article in Journal of cancer prevention, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Antioxidants (Basel, Switzerland) · 2026
    Review
  3. Nutraceutical Potential of Bitter Melon (Current issues in molecular biology · 2025
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kushal KandhariDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-8323-7278
Sandeep PaudelDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-6389-9485
Komal RainaDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0003-0371-1070
Chapla AgarwalDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0003-1146-4890
Rama KantDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-0550-1467
Michael F WempeDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-8157-5281
Cindy O'BryantDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0001-6337-2221
Rajesh AgarwalDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-9455-0235

Funding

Molecular mechanism of bitter melon juice efficacy against pancreatic cancer.R01CA195708 · NCI · UNIVERSITY OF COLORADO DENVER · PI AGARWAL, RAJESH · 2014 to 2018
$2.2M
NCI NIH HHS R01 CA195708
6 · The paper itself

Abstract

Given the high rates of incidence and mortality associated with pancreatic cancer (PanC), there is a need to develop alternative strategies to target PanC. Recent studies have demonstrated that fruits of bitter melon (

Indexed as

AngiogenesisApoptosisBitter melonNatural/dietary agentsPancreatic neoplasms

Identifiers

PMID35047453
PMCPMC8749318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.