Evidence map›Paper›PMID 35047416›Full record

ArticleFrontiers in cellular and infection microbiology2021

Clinical Performance of the Xpert

Yan Han, Mei-Qin Shi, Qing-Ping Jiang, Wen-Jing Le, Xiao-Lin Qin, Han-Zhen Xiong, He-Ping Zheng, Fred C Tenover, Yi-Wei Tang, Yue-Ping Yin

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Point-of-care Tests for Chlamydia trachomatis and Neisseria gonorrhoeae: Review of the Literature.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Pooled it
  2. Article
  3. Article
  4. Laboratory detection methods for Chlamydia trachomatis infection in children: a review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Rapid and simple detection of Chlamydia trachomatis and Neisseria gonorrhoeae using the EasyNAT CT/NG assay based on cross-priming amplification.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Yan HanInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Mei-Qin ShiInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Qing-Ping JiangDepatment of Pathology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Wen-Jing LeInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Xiao-Lin QinDermatology Hospital, Southern Medical University, Guangzhou, China.
Han-Zhen XiongDepatment of Pathology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
He-Ping ZhengDermatology Hospital, Southern Medical University, Guangzhou, China.
Fred C TenoverDepartment of Medical and Scientific Affairs, Cepheid, Sunnyvale, CA, United States.
Yi-Wei TangDepartment of Medical and Scientific Affairs, Danaher Diagnostic Platform China/Cepheid, Shanghai, China.
Yue-Ping YinInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNSouthern Medical University · CNThird Affiliated Hospital of Guangzhou Medical University · CNChinese Center For Disease Control and Prevention · CNDanaher (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We aimed to evaluate the clinical performance of the GeneXpert Methods: This study was conducted from September 2016 to September 2018 in three Chinese urban hospitals. The results from the Xpert CT/NG test were compared to those from the Roche cobas Results: In this study, 619 first void urine (FVU) specimens and 1,042 cervical swab specimens were included in the final dataset. There were no statistical differences between the results of the two tests for the detection of CT/NG in urine samples ( Conclusion: The Xpert CT/NG test exhibited high sensitivity and specificity in the detection of CT and NG in both urine and cervical samples when compared to the reference results. The 90-min turnaround time for CT and NG detection at the point of care using Xpert may enable patients to receive treatment promptly.

Indexed as

Chlamydia InfectionsGonorrheaChlamydia trachomatisFemaleHospitals, UrbanHumansNeisseria gonorrhoeaeSensitivity and SpecificityTomography, X-Ray Computedcervical swabsChlamydia trachomatismolecular testingNeisseria gonorrhoeaepoint-of-care testingurine

Identifiers

PMID35047416
PMCPMC8762110
OpenAlexW4205684416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.