Evidence map›Paper›PMID 35047384›Full record

ArticleFrontiers in oncology2021

Patterns-of-Care Analysis for Radiotherapy of Elderly Head-and-Neck Cancer Patients: A Trinational Survey in Germany, Austria and Switzerland.

Erik Haehl, Alexander Rühle, Simon Spohn, Tanja Sprave, Eleni Gkika, Constantinos Zamboglou, Anca-Ligia Grosu, Nils H Nicolay

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Erik HaehlDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Alexander RühleDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Simon SpohnDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Tanja SpraveDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Eleni GkikaDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Constantinos ZamboglouDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Anca-Ligia GrosuDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
Nils H NicolayDepartment of Radiation Oncology, University of Freiburg - Medical Center, Freiburg, Germany.
German Cancer Research Center · DEUniversity Medical Center Freiburg · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing, and clinical trials defining the standard of care either excluded or underrepresented elderly patients. This leaves physicians with a challenging and highly individual treatment decision largely lacking clinical evidence.

methodsA tri-national patterns-of-care survey was sent to all members of the German (DEGRO), Austrian (ÖGRO), and Swiss (SRO/SSRO) national societies of radiation oncology. The online questionnaire consisted of 27 questions on the treatment of elderly HNSCC patients, including 6 case-based questions. Frequency distributions and subgroup comparisons were calculated using SPSS statistics software.

resultsA total of 132 answers were collected, including 46(35%) form universities, 52(39%) from non-university-hospitals and 34(26%) from private practices. 83(63%) treat 1-5 and 42(32%) >5 elderly HNSCC patients per month. Target volumes are defined analog current guidelines by 65(50%) of responders and altered based on age/comorbidities or tumor stage by 36(28%) and 28(22%), respectively. Chemotherapy is routinely administered by 108(84%) if indicated, with weekly 40mg/m

conclusionTreatment of elderly HNSCC-patients in the German-speaking countries mainly follows guidelines established for younger patients. Algorithms for patient stratification and treatment de-escalation for "unfit" elderly patients are needed.

Indexed as

chemotherapyelderly patientsHNSCC (head and neck squamous cell carcinoma)patterns-of-careradiotherapy

Identifiers

PMID35047384
PMCPMC8761738
OpenAlexW4205302947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.