Evidence map›Paper›PMID 35047307›Full record

ArticleCureus2021

Frequency of Celiac Disease in Patients With Chronic Diarrhea.

Muhammad S Panezai, Asad Ullah, Kalyani Ballur, Lauren Gilstrap, Jaffar Khan, Bisma Tareen, Mirwais Kakar, Javeria Khan, Amna Rasheed, Abdul Waheed and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Celiac Disease: Beyond Diet and Food Awareness.Foods (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Who to screen and how to screen for celiac disease.World journal of gastroenterology · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Muhammad S PanezaiGastroenterology, Bolan Medical College, Quetta, PAK.
Asad UllahPathology, Medical College of Georgia, Augusta University, Augusta, USA.
Kalyani BallurClinical Oncology, Medical College of Georgia, Augusta University, Augusta, USA.
Lauren GilstrapPathology, Medical College of Georgia, Augusta University, Augusta, USA.
Jaffar KhanPathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
Bisma TareenInternal Medicine, Bolan Medical College, Quetta, PAK.
Mirwais KakarGastroenterology, Bolan Medical College, Quetta, PAK.
Javeria KhanGastroenterology, Holy Family Hospital, Rawalpindi, PAK.
Amna RasheedInternal Medicine, Touro University California, Vallejo, USA.
Abdul WaheedSurgery, San Joaquin General Hospital, French Camp, USA.
Intisar GhleilibPathology and Laboratory Medicine, Medical College of Georgia, Augusta University, Augusta, USA.
Joseph WhitePathology, Medical College of Georgia, Augusta University, Augusta, USA.
Frederick D CasonSurgery, San Joaquin General Hospital, French Camp, USA.
Augusta University · USBolan Medical College · PKSan Joaquin General Hospital · USHoly Family Hospital · PKIndiana University – Purdue University Indianapolis · USTouro University California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCeliac disease (CD) is an immune-mediated disease caused by ingesting gluten-containing foods and is characterized mainly by malabsorptive diarrhea. Furthermore, distinguishing between mild disease and asymptomatic individuals is critical and necessitates a high level of clinical suspicion. Short stature, delayed puberty, bone abnormalities, neurological problems, and intestinal cancer can all be consequences of a delayed diagnosis. This study aimed to determine the prevalence of celiac disease among our community's recurrent diarrhea patients.

methodsThis was a cross-sectional study aimed at determining the frequency of celiac disease in patients with chronic diarrhea. One hundred eighty-eight patients between the ages of 18 and 60 years who had chronic diarrhea lasting greater than three months were enrolled in this study. Stratification was utilized to control for modifiers. A p-value of ≤ 0.05 was considered significant.

resultsA total of 74.5% of patients (n=140) were male, while 25.5% (n=48) were female with a mean age of 38.48±10.85 years. The average duration of celiac disease symptoms was 8.17± 3.75 months. Celiac disease was found in 12.2% (n=23) of the individuals. Also, 21% of individuals with a positive family history of CD devolved CD, compared to those without prior CD family history (p=0.01).

conclusionsIn individuals with chronic diarrhea for more than three months, the prevalence of celiac disease was determined to be 12.2% (n=23). There was a statistically significant difference between those with a positive family history of CD and those who did not have the condition.

Indexed as

celiac diseasechronic diarrheadiagnosisgluten intoleranceprevalence

Identifiers

PMID35047307
PMCPMC8760010
OpenAlexW4200347742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.