Evidence map›Paper›PMID 35047227›Full record

ArticleCase reports in urology2022

Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal.

Kamal Ranabhat, Bhuvan Saud, Saroj Adhikari, Suraj Bhattarai, Rojan Adhikari, Bhoj Raj Luitel, Mahesh Raj Sigdel

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kamal RanabhatInstitue of Medicine, Tribhuvan University, Kathmandu, Nepal.
Bhuvan SaudDepartment of Medical Laboratory Technology, Janamaitri Foundation Institute of Health Sciences, Lalitpur, Nepal.ORCID https://orcid.org/0000-0002-3030-3382
Saroj AdhikariNational Trauma Center, Ministry of Health and Population Kathmandu, Nepal.
Suraj BhattaraiGlobal Institute for Interdisciplinary Studies, Kathmandu, Nepal.
Rojan AdhikariShahid Dharma Bhakta National Transplant Center, Bhaktapur, Nepal.
Bhoj Raj LuitelInstitue of Medicine, Tribhuvan University, Kathmandu, Nepal.
Mahesh Raj SigdelInstitue of Medicine, Tribhuvan University, Kathmandu, Nepal.
Tribhuvan University · NPBhaktapur Cancer Hospital · NPMinistry of Health and Population · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, SARS-CoV-2 has caused significant public health burden, mainly in patients with underlying comorbidities including both communicable and noncommunicable diseases. Solid organ transplant recipients under immunesupressive medication are also amongst the high risk group. There is only sparse data on immunity against SARS-CoV-2 infection among renal transplant recipients. In this case report, we present the level of anti-SARS-CoV-2 antibody of three kidney transplant recipients after vaccination against COVID-19 virus. All three cases had received two doses of Oxford-AstraZeneca COVID-19 vaccine AZD1222 (ChAdOx1). Serological analysis showed protective level of circulating antibodies in the blood of all three cases. Although two out of three patients in the study acquired COVID-19 infection after immunization, they recovered with mild clinical course. Hence, we conclude that despite immune-suppressed status of transplant recipients, COVID-19 vaccination could protect them against severe illness.

Identifiers

PMID35047227
PMCPMC8763547
OpenAlexW4206572904

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.