Evidence map›Paper›PMID 35047156›Full record

ArticleJournal of healthcare engineering2022

Study on the Mechanism of Platelet-Released Clusterins Inducing Restenosis after Carotid Endarterectomy by Activating TLR3/NF-

Qingyu Meng, Xichun Li, Mingyu Zhao, Shusen Lin, Xiangwen Yu, Guanglong Dong

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qingyu MengVascular Surgery Department, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID 0000-0003-4796-6358
Xichun LiVascular Surgery Department, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID 0000-0002-1654-9482
Mingyu ZhaoVascular Surgery Department, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID 0000-0003-0291-3746
Shusen LinVascular Surgery Department, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID 0000-0002-6486-7493
Xiangwen YuVascular Surgery Department, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID 0000-0002-2519-912X
Guanglong DongVascular Surgery Department, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID 0000-0002-1721-9098
Qiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore the role of clusterin released by platelet aggregation in restenosis after carotid endarterectomy. 35 patients who underwent carotid endarterectomy due to carotid artery stenosis were enrolled in this study. They were admitted to the Third Affiliated Hospital of Qiqihar Medical University from January 2018 to January 2019. All the patients were divided into two groups: the restenosis group and the nonrestenosis group, according to the follow-up results within 12 months. Peripheral blood was collected on the first day, 6 months, and 12 months after operation. The expression of CLU in serum of plasma and platelet culture medium was detected by an ELISA experiment. The vascular endothelial cells were cultured in vitro with 100 ng/mL of human recombinant CLU added to the medium. Cell proliferation, migration, and invasion were detected by CCK8, scratch, and Transwell invasion tests. The expression level of TLR3 and NF-

Indexed as

Endarterectomy, CarotidClusterinEndothelial CellsHumansNF-kappa BSignal TransductionToll-Like Receptor 3ClusterinNF-kappa BTLR3 protein, humanToll-Like Receptor 3

Identifiers

PMID35047156
PMCPMC8763522
OpenAlexW4206831535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.