Evidence map›Paper›PMID 35047020›Full record

ArticleFrontiers in genetics2021

VTP-Identifier: Vesicular Transport Proteins Identification Based on PSSM Profiles and XGBoost.

Yue Gong, Benzhi Dong, Zixiao Zhang, Yixiao Zhai, Bo Gao, Tianjiao Zhang, Jingyu Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yue GongCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Benzhi DongCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Zixiao ZhangCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Yixiao ZhaiCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Bo GaoDepartment of Radiology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Tianjiao ZhangCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Jingyu ZhangDepartment of Neurology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Northeast Forestry University · CNFourth Affiliated Hospital of Harbin Medical University · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vesicular transport proteins are related to many human diseases, and they threaten human health when they undergo pathological changes. Protein function prediction has been one of the most in-depth topics in bioinformatics. In this work, we developed a useful tool to identify vesicular transport proteins. Our strategy is to extract transition probability composition, autocovariance transformation and other information from the position-specific scoring matrix as feature vectors. EditedNearesNeighbours (ENN) is used to address the imbalance of the data set, and the Max-Relevance-Max-Distance (MRMD) algorithm is adopted to reduce the dimension of the feature vector. We used 5-fold cross-validation and independent test sets to evaluate our model. On the test set, VTP-Identifier presented a higher performance compared with GRU. The accuracy, Matthew's correlation coefficient (MCC) and area under the ROC curve (AUC) were 83.6%, 0.531 and 0.873, respectively.

Indexed as

machine learningposition-specific scoring matrixprotein function predictionvesicular transport proteinsXGBoost

Identifiers

PMID35047020
PMCPMC8762342
OpenAlexW4205205141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.